Miscellaneous ocular agents:

Indications for MACUGEN:

Treatment of neovascular (wet) age-related macular degeneration.


Give by intravitreous inj. 0.3mg once every 6 weeks into the eye to be treated.


Not recommended.


Ocular or periocular infections.


Monitor for infection during week following inj (endophthalmitis possible). Monitor intraocular pressure and perfusion of optic nerve. Pregnancy (Cat.B). Nursing mothers.

Pharmacologic Class:

Vascular endothelial growth factor (VEGF) inhibitor.

Adverse Reactions:

Anterior chamber inflammation, blurred vision, cataract, conjunctival hemorrhage, corneal edema, eye discharge, eye irritation, eye pain, hypertension, increased intraocular pressure, ocular discomfort, punctate keratitis, reduced visual acuity, visual disturbances, vitreous floaters, vitreous opacities, blepharitis, conjunctivitis, photopsia, bronchitis, diarrhea, dizziness, headache, nausea, UTI, others.

How Supplied:

Pre-filled syringe—1