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Macugen Generic Name & Formulations
Legal Class
Rx
General Description
Pegaptanib sodium 0.3mg/prefilled syringe; soln for oph intravitreous inj; preservative-free.
Pharmacological Class
Vascular endothelial growth factor (VEGF) inhibitor.
How Supplied
Pre-filled syringe—1
Manufacturer
Generic Availability
NO
Macugen Indications
Indications
Neovascular (wet) age-related macular degeneration.
Macugen Dosage and Administration
Adult
Give by intravitreous inj. 0.3mg once every 6 weeks into the eye to be treated.
Children
Not recommended.
Macugen Contraindications
Contraindications
Ocular or periocular infections.
Macugen Boxed Warnings
Not Applicable
Macugen Warnings/Precautions
Warnings/Precautions
Monitor for infection during week following inj (endophthalmitis possible). Monitor intraocular pressure and perfusion of optic nerve. Pregnancy (Cat.B). Nursing mothers.
Macugen Pharmacokinetics
See Literature
Macugen Interactions
Not Applicable
Macugen Adverse Reactions
Adverse Reactions
Anterior chamber inflammation, blurred vision, cataract, conjunctival hemorrhage, corneal edema, eye discharge, eye irritation, eye pain, hypertension, increased intraocular pressure, ocular discomfort, punctate keratitis, reduced visual acuity, visual disturbances, vitreous floaters, vitreous opacities, blepharitis, conjunctivitis, photopsia, bronchitis, diarrhea, dizziness, headache, nausea, UTI, others.
Macugen Clinical Trials
See Literature
Macugen Note
Not Applicable
Macugen Patient Counseling
See Literature
