Macugen

— THERAPEUTIC CATEGORIES —
  • Miscellaneous ocular agents

Macugen Generic Name & Formulations

General Description

Pegaptanib sodium 0.3mg/prefilled syringe; soln for oph intravitreous inj; preservative-free.

Pharmacological Class

Vascular endothelial growth factor (VEGF) inhibitor.

How Supplied

Pre-filled syringe—1

Generic Availability

NO

Macugen Indications

Indications

Neovascular (wet) age-related macular degeneration.

Macugen Dosage and Administration

Adult

Give by intravitreous inj. 0.3mg once every 6 weeks into the eye to be treated.

Children

Not recommended.

Macugen Contraindications

Contraindications

Ocular or periocular infections.

Macugen Boxed Warnings

Not Applicable

Macugen Warnings/Precautions

Warnings/Precautions

Monitor for infection during week following inj (endophthalmitis possible). Monitor intraocular pressure and perfusion of optic nerve. Pregnancy (Cat.B). Nursing mothers.

Macugen Pharmacokinetics

See Literature

Macugen Interactions

Not Applicable

Macugen Adverse Reactions

Adverse Reactions

Anterior chamber inflammation, blurred vision, cataract, conjunctival hemorrhage, corneal edema, eye discharge, eye irritation, eye pain, hypertension, increased intraocular pressure, ocular discomfort, punctate keratitis, reduced visual acuity, visual disturbances, vitreous floaters, vitreous opacities, blepharitis, conjunctivitis, photopsia, bronchitis, diarrhea, dizziness, headache, nausea, UTI, others.

Macugen Clinical Trials

See Literature

Macugen Note

Not Applicable

Macugen Patient Counseling

See Literature