• Muscle spasms

Lyvispah Generic Name & Formulations

General Description

Baclofen 5mg, 10mg, 20mg; oral granules; strawberry-flavor.

Pharmacological Class

Muscle relaxant (central).

How Supplied

Single-dose packets—90

Generic Availability


Lyvispah Indications


Spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity. May also be of some value in patients with spinal cord injuries and other spinal cord diseases.

Limitations of Use

Not for treatment of skeletal muscle spasm resulting from rheumatic disorders.

Lyvispah Dosage and Administration


Allow granules to dissolve in the mouth or can be swallowed. Also, can mix contents (1 packet) with up to 15mL of liquid or soft foods (eg, applesauce, yogurt, or pudding) if needed for administration within 2hrs. If multiple packets are required, each packet must be mixed with a separate volume of liquid or soft food. May also administer via enteral feeding tubes. Start with lowest dose possible; adjust based on response and tolerability. Initially 5mg 3 times daily for 3 days. May increase by increments of 5mg 3 times daily every 3 days, as needed; up to max 80mg daily.


<12yrs: not established.

Lyvispah Contraindications

Not Applicable

Lyvispah Boxed Warnings

Not Applicable

Lyvispah Warnings/Precautions


Avoid abrupt cessation. Withdraw gradually during discontinuation. Stroke. Psychotic disorders. Schizophrenia. Confusional states. Autonomic dysreflexia. Epilepsy. Beneficial spasticity. Renal impairment. Elderly. Neonatal withdrawal symptoms; gradually reduce dose and discontinue treatment prior to delivery. Pregnancy. Nursing mothers.

Lyvispah Pharmacokinetics

See Literature

Lyvispah Interactions


Additive CNS depression with alcohol, other CNS depressants.

Lyvispah Adverse Reactions

Adverse Reactions

Drowsiness, dizziness, weakness, nausea, confusion, hypotension, headache, insomnia, constipation, urinary frequency, fatigue; ovarian cysts, seizures and hallucinations on abrupt withdrawal.

Lyvispah Clinical Trials

See Literature

Lyvispah Note

Not Applicable

Lyvispah Patient Counseling

See Literature