Pituitary disorders:
Indications for LUPRON DEPOT-PED 3 MONTH:
Central precocious puberty.
Adult Dosage:
Not applicable.
Children Dosage:
<2yrs: not recommended. ≥2yrs: 11.25mg or 30mg as a single IM inj once every 3 months. If inadequate response, consider other alternative treatments.
LUPRON DEPOT-PED 3 MONTH Contraindications:
Pregnancy (Cat.X).
LUPRON DEPOT-PED 3 MONTH Warnings/Precautions:
Confirm diagnosis. Monitor for psychiatric symptoms. History of seizures/epilepsy, cerebrovascular disorders, CNS anomalies or tumors: risk of convulsions. Monitor hormonal effects after 1–2 months of starting therapy, with dose changes and during treatment. Depot 3-Month: monitor at months 2–3, month 6 and as needed thereafter. Measure height and bone age velocity every 6–12 months. Exclude pregnancy before treatment. Nursing mothers: not recommended.
See Also:
LUPRON DEPOT-PED 3 MONTH Classification:
GnRH analogue.
LUPRON DEPOT-PED 3 MONTH Interactions:
Caution with concomitant drugs that are associated with convulsions (eg, bupropion, SSRIs).
Adverse Reactions:
Transient exacerbation of symptoms, inj site reactions, pain, headache, emotional lability, hot flushes/sweating, acne/seborrhea, rash, vaginitis, vaginal discharge, syncope, GI upset, gynecomastia, weight increased, mood altered; convulsions.
How Supplied:
Depot-PED kit—1 (prefilled dual-chamber syringe w. diluent); Depot-PED 3 Month kit—1 (prefilled dual-chamber syringe w. diluent)