• Diarrhea

Loperamide Generic Name & Formulations

General Description

Loperamide HCl 2mg; caps.

Pharmacological Class


How Supplied

Caps—contact supplier; A-D Caplets—6, 12, 18, 24; A-D Liq—2oz, 4oz; Caplets, Chew tabs—contact supplier

Loperamide Indications



Loperamide Dosage and Administration


Acute: Initially 4mg, then 2mg after each loose stool; max 16mg/day. Stop after 48 hours if ineffective. Chronic: initially 4mg; maintenance 4–8mg/day. Reevaluate if no improvement after 10 days at 16mg/day.


<2yrs: not recommended. 24–47lbs (2–5yrs): 1mg up to 3 times daily for 2 days (use liq). 48–59lbs (6–8yrs): initially 2mg, then 1mg after each loose stool; max 4mg/day for 2 days. 60–95lbs (9–11yrs): initially 2mg, then 1mg after each loose stool; max 6mg/day for 2 days.

Loperamide Contraindications


If constipation must be avoided. Acute dysentery.

Loperamide Boxed Warnings

Not Applicable

Loperamide Warnings/Precautions


Acute ulcerative colitis and antibiotic induced pseudomembranous colitis; discontinue if abdominal distention occurs. In dehydration, use fluid and electrolyte replacement. Serious cardiac effects or death if taking more than directed. History of abnormal heart rhythm. Hepatic dysfunction; monitor for CNS toxicity. Pregnancy (Cat.B). Nursing mothers.

Loperamide Pharmacokinetics

See Literature

Loperamide Interactions

Not Applicable

Loperamide Adverse Reactions

Adverse Reactions

Abdominal pain, distention, constipation, dry mouth, nausea, drowsiness, dizziness, fatigue, rash.

Loperamide Clinical Trials

See Literature

Loperamide Note


Formerly known under the brand name Imodium.

Loperamide Patient Counseling

See Literature