• Topical steroids

Locoid Generic Name & Formulations

General Description

Hydrocortisone butyrate 0.1%; crm; oint.

Pharmacological Class


How Supplied

Crm, oint—15g, 45g; Lipocream—15g, 45g, 60g; Soln—20mL, 60mL

Locoid Indications


Corticosteroid-responsive dermatoses.

Locoid Dosage and Administration

Adults and Children

Apply thin film 2–3 times daily.

Locoid Contraindications


Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).

Locoid Boxed Warnings

Not Applicable

Locoid Warnings/Precautions


Treat infection if present; discontinue if infection persists or worsens. Do not use near eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.

Locoid Pharmacokinetics

See Literature

Locoid Interactions

Not Applicable

Locoid Adverse Reactions

Adverse Reactions

Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, HPA axis suppression (esp. in children).

Locoid Clinical Trials

See Literature

Locoid Note

Not Applicable

Locoid Patient Counseling

See Literature