Poisoning/overdose:

Indications for: KLOXXADO

Reversal of known or suspected opioid overdose, including respiratory and/or CNS depression.

Limitations of Use:

Not a substitute for emergency medical care.

Adults and Children:

Give as single spray intranasally into one nostril. May give additional doses (using a new nasal spray) every 2–3mins in alternate nostrils if unresponsive or relapses into respiratory depression. Seek immediate emergency medical assistance after the first dose.

KLOXXADO Warnings/Precautions:

Known or suspected opioid dependence; abrupt reversal may precipitate acute withdrawal syndrome. Monitor patients with satisfactory response due to long duration of some narcotics. Post-op use in pre-existing cardiac disease. Have other resuscitative measures available. Elderly. Pregnancy; monitor for neonatal withdrawal symptoms. Nursing mothers.

KLOXXADO Classification:

Opioid antagonist.

KLOXXADO Interactions:

Caution with cardiotoxic drugs. Incomplete reversal of buprenorphine or pentazocine; may require higher naloxone dose.

Adverse Reactions:

Abdominal pain, asthenia, dizziness, headache, nasal discomfort, presyncope; opioid withdrawal.

Generic Drug Availability:

NO

How Supplied:

Single-dose nasal spray—2

Pricing for KLOXXADO

two nasal spray devices of 8mg carton (Qty: 1)
Appx. price $135
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