• Miscellaneous diagnostic tests

Kinevac Generic Name & Formulations

General Description

Sincalide 5mcg; per vial; lyophilized pwd for IV inj after reconstitution; contains sodium metabisulfite.

Pharmacological Class

Cholecystopancreatic-gastrointestinal hormone peptide.

How Supplied



Kinevac Indications


To stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals. To stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology. To accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.

Kinevac Dosage and Administration


Give by IV inj. Gallbladder contraction: 0.02mcg/kg over 30–60secs; if unsatisfactory contraction after 15mins, may give second dose of 0.04mcg/kg. Pancreatic function test: 0.02mcg/kg infused over 30mins (start 30mins after secretin infusion). Barium meal transit: 0.04mcg/kg over 30–60secs; if unsatisfactory transit of barium meal after 30mins, may give second dose of 0.04mcg/kg.


Not established.

Kinevac Contraindications


Intestinal obstruction.

Kinevac Boxed Warnings

Not Applicable

Kinevac Warnings/Precautions


Have appropriate medical treatment readily available. Monitor for hypersensitivity reactions; discontinue if occur and do not restart. Small gallbladder stones (risk of lodging in cystic duct or common bile duct; rare). Labor & delivery. Pregnancy (Cat.B); spontaneous abortion or premature induction of labor may occur, do not give to women near term. Nursing mothers.

Kinevac Pharmacokinetics

See Literature

Kinevac Interactions

Not Applicable

Kinevac Adverse Reactions

Adverse Reactions

Abdominal discomfort/pain, nausea; anaphylaxis, other hypersensitivity reactions.

Kinevac Clinical Trials

See Literature

Kinevac Note

Not Applicable

Kinevac Patient Counseling

See Literature