• Vaccines

Kedrab Generic Name & Formulations

General Description

Rabies immune globulin (human) 150 IU/mL; soln for IM inj; preservative-free.

Pharmacological Class

Immune globulin.

How Supplied

Single-use vial (2mL, 10mL)—1


Generic Availability


Kedrab Indications


Post-exposure prophylaxis of rabies infection, to be given with a full course of rabies vaccine.

Kedrab Dosage and Administration


Prior to administration, follow recommendations for local treatment of wounds. Administer as soon as possible after exposure; may give up to 7 days after first vaccine dose. 20 IU/kg as single dose with first dose of rabies vaccine. If feasible, infiltrate dose into and around the wound; inj remainder into upper arm deltoid region. Avoid same inj site as rabies vaccine or repeat doses of Kedrab once vaccine treatment is initiated.


See full labeling.

Kedrab Contraindications

Not Applicable

Kedrab Boxed Warnings

Not Applicable

Kedrab Warnings/Precautions


Do not inj into gluteal region or blood vessel. History of complete pre- or post-exposure vaccination and confirmed adequate rabies titer: not recommended. Discontinue if allergic or anaphylactic reaction occurs; have epinephrine available. History of allergic reactions to human immunoglobulins; monitor. IgA deficiency. Increased risk of thrombosis with acquired or hereditary hypercoagulable states, prolonged immobilization, in-dwelling vascular catheters, older age, estrogen use, a history of venous or arterial thrombosis, cardiovascular risk factors, hyperviscosity syndromes; monitor for ≥24hrs post-injection. Increased risk of hemolysis with non-O blood group types, underlying inflammatory conditions, high cumulative doses of immune globulins. Contains human plasma; monitor for possible viral disease and variant Creutzfeldt-Jakob disease transmission. Pregnancy. Nursing mothers.

Kedrab Pharmacokinetics

See Literature

Kedrab Interactions


Avoid measles vaccine within 4 months of Kedrab; avoid other live attenuated vaccines within 3 months. May interfere with serologic tests (eg, Coombs’ test).

Kedrab Adverse Reactions

Adverse Reactions

Inj site pain, headache, muscle pain, upper respiratory tract infection; anaphylactic shock.

Kedrab Clinical Trials

See Literature

Kedrab Note

Not Applicable

Kedrab Patient Counseling

See Literature