Junel 24 Fe

  • Contraception

Junel 24 Fe Generic Name & Formulations

General Description

Norethindrone acetate 1mg, ethinyl estradiol 20mcg (24 light yellow tabs); inert+ (4 tabs); +contains ferrous fumarate 75mg.

Pharmacological Class

Progestin + estrogen.

How Supplied

Blister cards—3


Junel 24 Fe Indications


Oral contraception.

Junel 24 Fe Dosage and Administration


1 tab daily for 28 days; repeat.


Premenarchal: not recommended.

Junel 24 Fe Contraindications


Thrombophlebitis or thromboembolic disease. History of DVT, cerebrovascular or coronary artery disease. Thrombogenic valvular disease. Severe hypertension. Diabetes with vascular disease. Headaches with focal neurologic symptoms. Major surgery with prolonged immobilization. Known or suspected breast carcinoma, endometrial or other estrogen-dependent neoplasia. Undiagnosed abnormal genital bleeding. Pregnancy-related cholestasis. Hepatic disease or tumors. Pregnancy (Cat.X).

Junel 24 Fe Boxed Warnings

Boxed Warning

Cigarette smoking increases risk of serious cardiovascular events.

Junel 24 Fe Warnings/Precautions


Increased risk of cardiovascular events esp. in cigarette smokers >35yrs of age; not recommended. Discontinue if thrombotic event, unexplained visual changes, jaundice, or headache/migraine occurs, and at least 4 weeks before through 2 weeks after surgery associated with increased risk of thromboembolism, and during and after prolonged immobilization. Cardio- or cerebrovascular diseases. Gallbladder disease. Obesity. Diabetes. Prediabetes. Hypertriglyceridemia. Depression. Conditions aggravated by fluid retention; monitor. Evaluate significant changes in headaches, irregular uterine bleeding, amenorrhea, retinal vein thrombosis. Monitor BP. Do regular complete physical exams. Nursing mothers: not recommended.

Junel 24 Fe Pharmacokinetics

See Literature

Junel 24 Fe Interactions


May be antagonized by anti-infectives and anticonvulsants (eg, phenytoin, phenylbutazone, barbiturates, carbamazepine, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate), St. John’s wort; use backup contraception. May be potentiated by atorvastatin, acetaminophen, ascorbic acid, or CYP3A4 inhibitors (eg, itraconazole, ketoconazole). May be affected by HIV protease inhibitors. May antagonize acetaminophen, temazepam, salicylic acid, morphine, clofibric acid. May potentiate cyclosporine, prednisolone, theophylline. May affect laboratory tests (eg, coagulation factors, lipids, glucose tolerance, binding proteins, serum folate).

Junel 24 Fe Adverse Reactions

Adverse Reactions

Headache, vaginal candidiasis, upper respiratory tract infection, nausea, menstrual cramps, breast tenderness, sinusitis, bacterial vaginitis, abnormal cervical smear, acne, UTI, mood swings, weight gain, vomiting, metrorrhagia; serious cardiovascular events and stroke, vascular events, hypertension, irregular uterine bleeding, liver disease.

Junel 24 Fe Clinical Trials

See Literature

Junel 24 Fe Note

Not Applicable

Junel 24 Fe Patient Counseling

See Literature