Isopto Atropine

  • Miscellaneous ocular agents

Isopto Atropine Generic Name & Formulations

General Description

Atropine sulfate 1%; oph soln; contains benzalkonium chloride.

Pharmacological Class


How Supplied

Soln—5mL, 15mL

Isopto Atropine Indications


For mydriasis and/or cycloplegia. For cycloplegic refraction, for papillary dilation desired in inflammatory conditions of the iris and uveal tract.

Isopto Atropine Dosage and Administration


Compress lacrimal sac by digital pressure for 2–3 minutes after instillation to avoid excessive systemic absorption. Uveitis: 1–2 drops in the eye(s) up to 4 times daily. Heavily pigmented irides may require larger doses.


Not established.

Isopto Atropine Contraindications


Primary glaucoma or tendency toward glaucoma (eg, narrow anterior chamber angle).

Isopto Atropine Boxed Warnings

Not Applicable

Isopto Atropine Warnings/Precautions


Previous susceptibility to belladonna alkaloids; excessive use may produce systemic symptoms of atropine poisoning. Estimate depth of angle of anterior chamber to avoid inducing angle closure glaucoma. Infants. Pregnancy (Cat.C). Nursing mothers.

Isopto Atropine Pharmacokinetics

See Literature

Isopto Atropine Interactions

Not Applicable

Isopto Atropine Adverse Reactions

Adverse Reactions

Prolonged use: follicular conjunctivitis, vascular congestion, edema, exudate, eczematoid dermatitis; hypotension, progressive respiratory depression (with excessive systemic absorption); children: coma, death possible.

Isopto Atropine Clinical Trials

See Literature

Isopto Atropine Note

Not Applicable

Isopto Atropine Patient Counseling

See Literature