• Vaccines

Ipol Generic Name & Formulations

General Description

Trivalent poliovirus vaccine; inactivated; whole virus grown in monkey kidney cells; IM or SC inj.

Pharmacological Class


How Supplied

Syringe 0.5mL (w. needle)—1, 10; Multidose vial (10 doses)—1


Ipol Indications


Poliomyelitis immunization (virus Types 1, 2, and 3).

Ipol Dosage and Administration


Inject IM or SC in deltoid area. Each dose is 0.5mL. Previously unvaccinated: Two doses at a 1–2 month interval and a third dose 6–12 months later. Incompletely vaccinated: give 1–2 doses to complete series. Completely vaccinated: may give booster dose.


Inject IM or SC in midlateral thigh. Each dose is 0.5mL. Under 6 wks: not recommended. Full IPV schedule: One dose at 2 months, 4 months, 6–18 months, and 4–6 years of age. Sequential schedule with oral polio vaccine (OPV) (do not use OPV for immunocompromised patients or patients with immunocompromised household contacts): One dose of IPOL at 2 months and at 4 months of age, then 1 dose of OPV at 12–18 months and 1 dose of OPV at 4–6 years of age.

Ipol Contraindications


Hypersensitivity to neomycin, streptomycin, or polymyxin B. May defer in acute febrile illness.

Ipol Boxed Warnings

Not Applicable

Ipol Warnings/Precautions


Have epinephrine inj (1:1000) available. Immunodeficiency. Pregnancy (Cat.C). Nursing mothers.

Ipol Pharmacokinetics

See Literature

Ipol Interactions


Immunosuppressants: may get suboptimal response.

Ipol Adverse Reactions

Adverse Reactions

Local irritation, fever, sleepiness, fussiness, decreased appetite.

Ipol Clinical Trials

See Literature

Ipol Note

Not Applicable

Ipol Patient Counseling

See Literature