Ipol Generic Name & Formulations
Legal Class
Rx
General Description
Trivalent poliovirus vaccine; inactivated; whole virus grown in monkey kidney cells; IM or SC inj.
Pharmacological Class
IPV.
How Supplied
Syringe 0.5mL (w. needle)—1, 10; Multidose vial (10 doses)—1
Manufacturer
Ipol Indications
Indications
Poliomyelitis immunization (virus Types 1, 2, and 3).
Ipol Dosage and Administration
Adult
Inject IM or SC in deltoid area. Each dose is 0.5mL. Previously unvaccinated: Two doses at a 1–2 month interval and a third dose 6–12 months later. Incompletely vaccinated: give 1–2 doses to complete series. Completely vaccinated: may give booster dose.
Children
Inject IM or SC in midlateral thigh. Each dose is 0.5mL. Under 6 wks: not recommended. Full IPV schedule: One dose at 2 months, 4 months, 6–18 months, and 4–6 years of age. Sequential schedule with oral polio vaccine (OPV) (do not use OPV for immunocompromised patients or patients with immunocompromised household contacts): One dose of IPOL at 2 months and at 4 months of age, then 1 dose of OPV at 12–18 months and 1 dose of OPV at 4–6 years of age.
Ipol Contraindications
Contraindications
Hypersensitivity to neomycin, streptomycin, or polymyxin B. May defer in acute febrile illness.
Ipol Boxed Warnings
Not Applicable
Ipol Warnings/Precautions
Warnings/Precautions
Have epinephrine inj (1:1000) available. Immunodeficiency. Pregnancy (Cat.C). Nursing mothers.
Ipol Pharmacokinetics
See Literature
Ipol Interactions
Interactions
Immunosuppressants: may get suboptimal response.
Ipol Adverse Reactions
Adverse Reactions
Local irritation, fever, sleepiness, fussiness, decreased appetite.
Ipol Clinical Trials
See Literature
Ipol Note
Not Applicable
Ipol Patient Counseling
See Literature