Anemias:

Indications for: INJECTAFER

Iron deficiency anemia in adults who have intolerance or insufficient response to oral iron; or have non-dialysis-dependent chronic kidney disease.

Adult Dosage:

Give by slow IV push (undiluted) at rate of approx. 100mg (2mL)/min; or by IV infusion (diluted) administered over at least 15mins. When giving via IV infusion, dilute to concentration not less than 2mg iron/mL. <50kg: 15mg/kg/dose in 2 doses separated by ≥7 days. ≥50kg: 750mg/dose in 2 doses separated by ≥7 days (total cumulative dose per course: 1500mg) or 15mg/kg (up to max 1000mg) as a single-dose. May repeat treatment if condition reoccurs.

Children Dosage:

Not established.

INJECTAFER Warnings/Precautions:

Monitor for hypersensitivity reactions during and after administration for ≥30mins and until clinically stable. Have epinephrine inj immediately available. Possible risk for hypophosphatemia if history of GI disorders associated with malabsorption of fat-soluble vitamins or phosphate, hyperparathyroidism, vitamin D deficiency, malnutrition. Monitor serum phosphate levels in at-risk patients who require a repeat course. Monitor for hypertension after each administration. Avoid extravasation. Neonates. Pregnancy: risk of fetal bradycardia (esp. during 2nd & 3rd trimester). Nursing mothers.

INJECTAFER Classification:

Hematinic.

INJECTAFER Interactions:

Possible risk for hypophosphatemia with concurrent or prior use of drugs that affect proximal renal tubular function. Lab assays may overestimate serum iron and transferrin bound iron within 24hrs after administration.

Adverse Reactions:

Nausea, hypertension, flushing, hypophosphatemia, dizziness; rare: hypersensitivity reactions.

Generic Drug Availability:

NO

How Supplied:

Single-dose vial (15mL)—1

Pricing for INJECTAFER

15ml of 750mg/15ml vial (Qty: 1)
Appx. price $1207
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