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Imovax Generic Name & Formulations
Legal Class
Rx
General Description
Rabies vaccine 2.5Units/mL; grown in human diploid cell cultures (inactivated whole virus); inj.
How Supplied
Single-dose vial (1mL)—1 (w. syringe and diluent)
Manufacturer
Imovax Indications
Indications
Preexposure immunization and postexposure treatment of rabies.
Imovax Dosage and Administration
Adults and Children
Preexposure: 3 inj of 1mL IM each on day 0, 7, and either day 21 or 28. Booster doses: 1mL every 2 yrs (see literature). Postexposure treatment: a 5 dose regimen of 1mL IM given on days 0, 3, 7, 14, 28 or 30 (WHO or ACIP recommendations), and 90 (give 1st dose with rabies immune globulin). If previously immunized against rabies, only 2 doses are given, immediately after exposure, and 3 days later (no rabies immune globulin needed).
Imovax Contraindications
Not Applicable
Imovax Boxed Warnings
Not Applicable
Imovax Warnings/Precautions
Warnings/Precautions
Postpone preexposure immunization during acute febrile illness or infection. Immunocompromised: may get suboptimal response (monitor titers). Have epinephrine inj (1:1000) available. Pregnancy (Cat.C).
Imovax Pharmacokinetics
See Literature
Imovax Interactions
Interactions
Immunosuppressants: may get suboptimal response.
Imovax Adverse Reactions
Adverse Reactions
Local reactions (pain, erythema, swelling), systemic reactions (nausea, headache, muscle aches, abdominal pain).
Imovax Clinical Trials
See Literature
Imovax Note
Not Applicable
Imovax Patient Counseling
See Literature
