Ibsrela Generic Name & Formulations
Tenapanor (as HCl) 50mg; tabs.
Sodium/hydrogen exchanger 3 (NHE3) inhibitor.
Irritable bowel syndrome with constipation (IBS-C).
Ibsrela Dosage and Administration
Take immediately prior to breakfast (or the first meal of the day) and prior to dinner. 50mg twice daily.
<18yrs: not established.
Patients <6yrs of age. Known or suspected mechanical GI obstruction.
Ibsrela Boxed Warnings
Avoid use in patients 6–<12yrs of age. Suspend dosing and rehydrate if severe diarrhea occurs. Pregnancy. Nursing mothers.
Antagonizes OATP2B1 substrates (eg, enalapril); monitor and increase dosage of substrates as needed.
Ibsrela Adverse Reactions
Diarrhea, abdominal distension, flatulence, dizziness.
Ibsrela Clinical Trials
Ibsrela Patient Counseling