Hyoscyamine Sulfate Drops

  • Hyperacidity, GERD, and ulcers

Hyoscyamine Sulfate Drops Generic Name & Formulations

General Description

Hyoscyamine sulfate 0.125mg/mL; alcohol 5%; orange flavor.

Pharmacological Class


See Also

How Supplied

Tabs, SL—100, 500; Drops—contact supplier

Hyoscyamine Sulfate Drops Indications


Adjunct in peptic ulcer. Irritable bowel syndrome. Infant colic.

Hyoscyamine Sulfate Drops Dosage and Administration


1–2mL every 4 hrs or as needed; max 12mL/day.


3.4kg: 4 drops. 5kg: 5 drops. 7kg: 6 drops. 10kg: 8 drops. Older children (2 yrs–12 yrs): 0.25–1mL; max 6mL/day. All: every 4 hrs or as needed.

Hyoscyamine Sulfate Drops Contraindications


Glaucoma. Unstable cardiovascular status in acute hemorrhage. GI or urinary tract obstruction. Paralytic ileus, intestinal atony of elderly or debilitated patients. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis.

Hyoscyamine Sulfate Drops Boxed Warnings

Not Applicable

Hyoscyamine Sulfate Drops Warnings/Precautions


High environmental temperature. Diarrhea. Autonomic neuropathy. Impaired cardiac or renal function. Cardiovascular disease. Hypertension. Hyperthyroidism. Hiatal hernia with reflux esophagitis. Pregnancy (Cat.C). Nursing mothers.

Hyoscyamine Sulfate Drops Pharmacokinetics

See Literature

Hyoscyamine Sulfate Drops Interactions


Antacids may inhibit absorption. Additive anticholinergic effects with other anticholinergics, amantadine, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics, MAOIs.

Hyoscyamine Sulfate Drops Adverse Reactions

Adverse Reactions

Anticholinergic effects, drowsiness.

Hyoscyamine Sulfate Drops Clinical Trials

See Literature

Hyoscyamine Sulfate Drops Note


Formerly known under the brand name Levsin Drops.

Hyoscyamine Sulfate Drops Patient Counseling

See Literature