• Cough and cold

Hycofenix Generic Name & Formulations

General Description

Hydrocodone bitartrate 2.5mg, pseudoephedrine HCl 30mg, guaifenesin 200mg; per 5mL; oral soln; black raspberry flavor.

Pharmacological Class

Antitussive + sympathomimetic + expectorant.

How Supplied

Soln—118mL, 473mL

Generic Availability


Hycofenix Indications


Cough, nasal congestion, and to loosen mucus associated with the common cold.

Hycofenix Dosage and Administration


Use accurate measuring device. ≥18yrs: 10mL every 4–6hrs. Max 4 doses (40mL) in 24hrs.


<18yrs: not established.

Hycofenix Contraindications


During or within 14 days of MAOIs. Narrow angle glaucoma. Urinary retention. Severe hypertension. Severe coronary artery disease.

Hycofenix Boxed Warnings

Not Applicable

Hycofenix Warnings/Precautions


Risks from concomitant use with benzodiazepines or other CNS depressants (see Interactions). Discontinue if respiratory depression occurs. Drug dependence. Abuse potential (monitor). Avoid in head injury, other intracranial lesions or pre-existing increase in intracranial pressure. Acute abdomen. Cardiovascular disorders. Persistent or chronic cough (eg, smoking, asthma, chronic bronchitis, emphysema) or if excessive phlegm: not recommended. Diabetes. Thyroid disorders. Addison's disease. Prostatic hypertrophy. Urethral stricture. Asthma. Severe hepatic or renal impairment. Elderly. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Hycofenix Pharmacokinetics

See Literature

Hycofenix Interactions


See Contraindications. Increased risk of respiratory depression, sedation with benzodiazepines or other CNS depressants (eg, opioids, antihistamines, antipsychotics, anxiolytics, alcohol); avoid. Hypertensive crisis with MAOIs. May affect or be affected by TCAs. Paralytic ileus may occur with anticholinergics.

Hycofenix Adverse Reactions

Adverse Reactions

Dizziness, headache, sedation, nausea, decreased blood pressure; respiratory depression, cardiovascular effects.

Hycofenix Clinical Trials

See Literature

Hycofenix Note

Not Applicable

Hycofenix Patient Counseling

See Literature