Constipation and bowel cleansers:

Indications for: GoLYTELY

Bowel cleansing before colonscopy and barium enema x-ray examination.

Adult Dosage:

May consume water or clear liquids during and after completion of bowel prep up until 2hrs before procedure. Drink 240mL orally every 10 mins or 20–30mL/min by NG tube until rectal effluent is clear or 1 gallon consumed. May interrupt if severe GI disturbances occur.

Children Dosage:

Not established.

GoLYTELY Contraindications:

GI obstruction. Bowel perforation. Gastric retention. Ileus. Toxic colitis or megacolon.

GoLYTELY Warnings/Precautions:

Not for direct ingestion. Correct fluid/electrolyte abnormalities prior to initiation. History of prolonged QT, uncontrolled arrhythmias, recent MI, unstable angina, CHF, or cardiomyopathy: increased risk of arrhythmias; consider ECGs at pre-dose and post-colonoscopy. History or risk of seizures. Renal impairment: monitor baseline and post-colonoscopy electrolytes, creatinine, BUN. Inflammatory bowel disease. Rule out suspected GI obstruction/perforation before administering. Severe ulcerative colitis. Impaired gag reflex. Semi- or unconscious patients. Risk for regurgitation or aspiration. Maintain adequate hydration. Pregnancy. Nursing mothers.

GoLYTELY Classification:

Isosmotic bowel cleanser.

GoLYTELY Interactions:

Avoid concomitant with starch-based thickeners. Caution with drugs that increase risk of fluid/electrolyte abnormalities, arrhythmias or QT prolongation. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal, known or suspected hyponatremia: may increase risk of seizures. Concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Avoid concomitant stimulant laxatives (eg, bisacodyl, sodium picosulfate). Oral drugs administered within 1hr of start of Golytely may not be absorbed.

Adverse Reactions:

Nausea, abdominal fullness, bloating, cramps, vomiting, anal irritation; seizures, arrhythmias, mucosal ulcerations and ischemic colitis, hypersensitivity reactions.

Generic Drug Availability:

YES

How Supplied:

Disposable jug (4L)—1