Imaging agents:

Indications for GLEOLAN:

As an adjunct for the visualization of malignant tissue during surgery in patients with glioma (suspected WHO Grades III or IV on pre-op imaging).


See full labeling. Administer 20mg/kg orally 3hrs (range 2–4hrs) prior to anesthesia.


Not established.


Porphyrin hypersensitivity. Acute or chronic porphyria.


Should only be used by trained neurosurgeons. Reduce exposure to sunlight or room lights for 48hrs after administration. Risk of misinterpretation (including false [–] and [+]). Have CPR equipment and personnel available to manage hypersensitivity reactions; monitor. Renal and hepatic impairment. Pregnancy. Nursing mothers: pump and discard breast milk for 24hrs after dose.

Pharmacologic Class:

Optical imaging agent.


Risk of phototoxic reactions with phototoxic drugs (eg, St. John’s wort, griseofulvin, thiazide diuretics, sulfonylureas, phenothiazines, sulfonamides, quinolones, tetracyclines, ALA-containing topical preps); avoid for 24hrs before and after Gleolan.

Adverse Reactions:

Pyrexia, hypotension, nausea, vomiting, chills, photosensitivity reaction, solar dermatitis, abnormal LFTs, diarrhea, neurologic events (eg, aphasia, hemiparesis, hemianopia, headache, seizure, hemiplegia, monoparesis, hypoesthesia), brain edema, elevated liver enzymes.

Generic Availability:


How Supplied:


Pricing for GLEOLAN

50ml of 1,500mg vial (Qty: 1)
Appx. price $2854