Fortaz

— THERAPEUTIC CATEGORIES —
  • Bacterial infections

Fortaz Generic Name & Formulations

General Description

Ceftazidime 500mg, 1g, 2g; IM or IV inj; sodium content 2.3mEq/g.

Pharmacological Class

Cephalosporin.

How Supplied

Vials—10

Manufacturer

Fortaz Indications

Indications

Susceptible infections including septicemia, pneumonia, skin and skin structure, bone and joint, gynecologic, intraabdominal, meningitis, urinary tract.

Fortaz Dosage and Administration

Adult

Uncomplicated UTIs: 250mg IV or IM every 12hrs. Complicated UTIs: 500mg IV or IM every 8–12hrs. Uncomplicated pneumonia, mild skin or skin structure: 500mg–1g IV or IM every 8hrs. Bone and joint: 2g IV every 12hrs. Serious gynecologic, intraabdominal, meningitis, or very severe life-threatening (esp. immunocompromised): 2g IV every 8hrs. Lung infections by Pseudomonas in cystic fibrosis: 30–50mg/kg IV every 8hrs (max 6g/day). Renal impairment: CrCl 31–50mL/min: 1g every 12hrs; CrCl 16–30mL/min: 1g every 24hrs; CrCl 6–15mL/min: 500mg every 24hrs; CrCl <5mL/min: 500mg every 48hrs. Hemodialysis: 1g loading dose then 1g after dialysis session. Peritoneal dialysis: 1g loading dose then 500mg every 24hrs.

Children

Neonates: 30mg/kg IV every 12hrs. 1mo–12yrs: 30–50mg/kg IV every 8hrs (max 6g/day). Renal impairment: reduce dose.

Fortaz Contraindications

Not Applicable

Fortaz Boxed Warnings

Not Applicable

Fortaz Warnings/Precautions

Warnings/Precautions

Penicillin or other allergy. Renal impairment; see Adult. Monitor prothrombin time in renal or hepatic dysfunction, poor nutritional states, or long-term use. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.

Fortaz Pharmacokinetics

See Literature

Fortaz Interactions

Interactions

May potentiate nephrotoxicity of aminoglycosides or diuretics. Antagonized by chloramphenicol. False (+) glucose test with Clinitest, Benedict's, or Fehling's soln.

Fortaz Adverse Reactions

Adverse Reactions

Hypersensitivity reactions (eg, rash, pruritus, fever), local reactions, GI upset, elevated liver enzymes; C. difficile-associated diarrhea.

Fortaz Clinical Trials

See Literature

Fortaz Note

Not Applicable

Fortaz Patient Counseling

See Literature