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Fortaz Generic Name & Formulations
Legal Class
Rx
General Description
Ceftazidime 500mg, 1g, 2g; IM or IV inj; sodium content 2.3mEq/g.
Pharmacological Class
Cephalosporin.
How Supplied
Vials—10
Manufacturer
Fortaz Indications
Indications
Susceptible infections including septicemia, pneumonia, skin and skin structure, bone and joint, gynecologic, intraabdominal, meningitis, urinary tract.
Fortaz Dosage and Administration
Adult
Uncomplicated UTIs: 250mg IV or IM every 12hrs. Complicated UTIs: 500mg IV or IM every 8–12hrs. Uncomplicated pneumonia, mild skin or skin structure: 500mg–1g IV or IM every 8hrs. Bone and joint: 2g IV every 12hrs. Serious gynecologic, intraabdominal, meningitis, or very severe life-threatening (esp. immunocompromised): 2g IV every 8hrs. Lung infections by Pseudomonas in cystic fibrosis: 30–50mg/kg IV every 8hrs (max 6g/day). Renal impairment: CrCl 31–50mL/min: 1g every 12hrs; CrCl 16–30mL/min: 1g every 24hrs; CrCl 6–15mL/min: 500mg every 24hrs; CrCl <5mL/min: 500mg every 48hrs. Hemodialysis: 1g loading dose then 1g after dialysis session. Peritoneal dialysis: 1g loading dose then 500mg every 24hrs.
Children
Neonates: 30mg/kg IV every 12hrs. 1mo–12yrs: 30–50mg/kg IV every 8hrs (max 6g/day). Renal impairment: reduce dose.
Fortaz Contraindications
Not Applicable
Fortaz Boxed Warnings
Not Applicable
Fortaz Warnings/Precautions
Warnings/Precautions
Penicillin or other allergy. Renal impairment; see Adult. Monitor prothrombin time in renal or hepatic dysfunction, poor nutritional states, or long-term use. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.
Fortaz Pharmacokinetics
See Literature
Fortaz Interactions
Interactions
May potentiate nephrotoxicity of aminoglycosides or diuretics. Antagonized by chloramphenicol. False (+) glucose test with Clinitest, Benedict's, or Fehling's soln.
Fortaz Adverse Reactions
Adverse Reactions
Hypersensitivity reactions (eg, rash, pruritus, fever), local reactions, GI upset, elevated liver enzymes; C. difficile-associated diarrhea.
Fortaz Clinical Trials
See Literature
Fortaz Note
Not Applicable
Fortaz Patient Counseling
See Literature
