Fluzone High-dose Quadrivalent

— THERAPEUTIC DISORDERS TREATED —
  • Vaccines

Fluzone High-dose Quadrivalent Generic Name & Formulations

General Description

Quadrivalent inactivated "split virus" influenza vaccine (Types A and B); 0.7mL dose contains a total of 240mcg of influenza virus hemagglutinin; formulation changes annually; susp for IM inj; antibiotic- and preservative-free.

Pharmacological Class

Influenza vaccine.

How Supplied

Fluzone High-Dose Quadrivalent prefilled syringe (0.7mL)—10; Fluzone Quadrivalent prefilled syringe (0.25mL, 0.5mL)—10; single-dose vial (0.5mL)—10; multi-dose vial (5mL)—1 (contains thimerosal)

Manufacturer

Generic Availability

NO

Fluzone High-dose Quadrivalent Indications

Indications

Influenza immunization for patients aged ≥65yrs.

Fluzone High-dose Quadrivalent Dosage and Administration

Adult

<65yrs: use Fluzone Quadrivalent. Give by IM inj once in the deltoid. ≥65yrs: 1 dose/season.

Children

Use Fluzone Quadrivalent.

Fluzone High-dose Quadrivalent Contraindications

Contraindications

Allergy to egg proteins. Life-threatening reaction to any previous flu vaccine.

Fluzone High-dose Quadrivalent Boxed Warnings

Not Applicable

Fluzone High-dose Quadrivalent Warnings/Precautions

Warnings/Precautions

Use current formulation only. Guillain-Barre syndrome within 6 weeks of previous flu vaccine. Immunosuppressed. Have epinephrine inj (1:1000) available. Pregnancy. Nursing mothers.

Fluzone High-dose Quadrivalent Pharmacokinetics

See Literature

Fluzone High-dose Quadrivalent Interactions

Interactions

Immunosuppressants: may get suboptimal response.

Fluzone High-dose Quadrivalent Adverse Reactions

Adverse Reactions

Local reactions (eg, pain, tenderness, swelling, erythema), malaise, headache, myalgia, irritability.

Fluzone High-dose Quadrivalent Clinical Trials

See Literature

Fluzone High-dose Quadrivalent Note

Not Applicable

Fluzone High-dose Quadrivalent Patient Counseling

See Literature