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Fluzone High-dose Quadrivalent Generic Name & Formulations
Legal Class
Rx
General Description
Quadrivalent inactivated "split virus" influenza vaccine (Types A and B); 0.7mL dose contains a total of 240mcg of influenza virus hemagglutinin; formulation changes annually; susp for IM inj; antibiotic- and preservative-free.
Pharmacological Class
Influenza vaccine.
See Also
How Supplied
Fluzone High-Dose Quadrivalent prefilled syringe (0.7mL)—10; Fluzone Quadrivalent prefilled syringe (0.25mL, 0.5mL)—10; single-dose vial (0.5mL)—10; multi-dose vial (5mL)—1 (contains thimerosal)
Manufacturer
Generic Availability
NO
Fluzone High-dose Quadrivalent Indications
Indications
Influenza immunization for patients aged ≥65yrs.
Fluzone High-dose Quadrivalent Dosage and Administration
Adult
<65yrs: use Fluzone Quadrivalent. Give by IM inj once in the deltoid. ≥65yrs: 1 dose/season.
Children
Use Fluzone Quadrivalent.
Fluzone High-dose Quadrivalent Contraindications
Contraindications
Allergy to egg proteins. Life-threatening reaction to any previous flu vaccine.
Fluzone High-dose Quadrivalent Boxed Warnings
Not Applicable
Fluzone High-dose Quadrivalent Warnings/Precautions
Warnings/Precautions
Use current formulation only. Guillain-Barre syndrome within 6 weeks of previous flu vaccine. Immunosuppressed. Have epinephrine inj (1:1000) available. Pregnancy. Nursing mothers.
Fluzone High-dose Quadrivalent Pharmacokinetics
See Literature
Fluzone High-dose Quadrivalent Interactions
Interactions
Immunosuppressants: may get suboptimal response.
Fluzone High-dose Quadrivalent Adverse Reactions
Adverse Reactions
Local reactions (eg, pain, tenderness, swelling, erythema), malaise, headache, myalgia, irritability.
Fluzone High-dose Quadrivalent Clinical Trials
See Literature
Fluzone High-dose Quadrivalent Note
Not Applicable
Fluzone High-dose Quadrivalent Patient Counseling
See Literature
