Fluphenazine Concentrate

  • Psychosis

Fluphenazine Concentrate Generic Name & Formulations

General Description

Fluphenazine HCl 5mg/mL; alcohol 14%. Dilute just before administration.

Pharmacological Class

Piperazine phenothiazine.

How Supplied

Contact supplier.

Fluphenazine Concentrate Indications



Fluphenazine Concentrate Dosage and Administration


Initially: 2.5–10mg daily in 3–4 divided doses; max 40mg daily.


Not recommended.

Fluphenazine Concentrate Contraindications


Coma. CNS or bone marrow depression. Liver disease. Subcortical brain damage. Blood dyscrasias.

Fluphenazine Concentrate Boxed Warnings

Not Applicable

Fluphenazine Concentrate Warnings/Precautions


Cardiovascular or renal disease. Pheochromocytoma. Seizures. Glaucoma. History of breast cancer. Exposure to extreme heat or organophosphates. Gradually reduce to lowest effective maintenance dose. Monitor blood, liver, renal, and ocular function. Mental retardation. Surgery. Pregnancy. Nursing mothers.

Fluphenazine Concentrate Pharmacokinetics

See Literature

Fluphenazine Concentrate Interactions


Potentiates anticholinergics, CNS depression with alcohol and other CNS depressants; both drugs with propranolol. Antagonized by anticholinergics. Decreased guanethidine effects. May cause false (+) pregnancy test.

Fluphenazine Concentrate Adverse Reactions

Adverse Reactions

Drowsiness, anticholinergic and other autonomic effects, insomnia, restlessness, rash, photosensitivity, tardive dyskinesia, blood dyscrasias, jaundice, pneumonia, hypertension, retinopathy, lowered seizure threshold, extrapyramidal reactions, neuroleptic malignant syndrome, weight changes, endocrine effects.

Fluphenazine Concentrate Clinical Trials

See Literature

Fluphenazine Concentrate Note


Formerly known under the brand names Prolixin (tabs, concentrate, elixir, inj); Permitil (tabs, concentrate); Prolixin Decanoate (decanoate inj).

Fluphenazine Concentrate Patient Counseling

See Literature