Flumist Quadrivalent

  • Vaccines

Flumist Quadrivalent Generic Name & Formulations

General Description

Quadrivalent, live attenuated influenza vaccine (virus types A and B); formulation changes annually; susp in intranasal sprayer; contains gelatin, arginine, gentamicin (trace); preservative-free.

Pharmacological Class

Influenza vaccine.

How Supplied

Single-dose pre-filled nasal spray (0.2mL)—10


Flumist Quadrivalent Indications


Influenza immunization.

Flumist Quadrivalent Dosage and Administration

Adults and Children

<2yrs or ≥50yrs: not recommended. Give before start of flu season; each dose is 0.2mL intranasally (as 0.1mL/nostril). 2–8yrs: 1 or 2 doses/season (depends on vaccination history as per annual ACIP recommendation); if 2 doses, give at least 1 month apart. 9–49yrs: 1 dose/season.

Flumist Quadrivalent Contraindications


Allergy to egg protein, gentamicin, gelatin, or arginine. Life-threatening reaction to previous flu vaccine. Concomitant aspirin in patients 2–17yrs of age (Reye's syndrome).

Flumist Quadrivalent Boxed Warnings

Not Applicable

Flumist Quadrivalent Warnings/Precautions


Use current formulation only. Asthmatics or children <5yrs old with recurrent wheezing: may be at increased risk of wheezing following administration. Guillain-Barre syndrome within 6 weeks of previous flu vaccine. Underlying medical conditions predisposing to flu complications. Immunocompromised. Have epinephrine inj (1:1000) available. Pregnancy. Nursing mothers.

Flumist Quadrivalent Pharmacokinetics

See Literature

Flumist Quadrivalent Interactions


Concomitant vaccines: see full labeling. Do not administer until 48hrs after antiviral therapy cessation. Do not give antivirals within 2 weeks of administration.

Flumist Quadrivalent Adverse Reactions

Adverse Reactions

Rhinorrhea/nasal congestion, fever, sore throat, decreased appetite, irritability; wheezing.

Flumist Quadrivalent Clinical Trials

See Literature

Flumist Quadrivalent Note

Not Applicable

Flumist Quadrivalent Patient Counseling

See Literature