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Flumist Quadrivalent Generic Name & Formulations
Legal Class
Rx
General Description
Quadrivalent, live attenuated influenza vaccine (virus types A and B); formulation changes annually; susp in intranasal sprayer; contains gelatin, arginine, gentamicin (trace); preservative-free.
Pharmacological Class
Influenza vaccine.
How Supplied
Single-dose pre-filled nasal spray (0.2mL)—10
Manufacturer
Flumist Quadrivalent Indications
Indications
Influenza immunization.
Flumist Quadrivalent Dosage and Administration
Adults and Children
<2yrs or ≥50yrs: not recommended. Give before start of flu season; each dose is 0.2mL intranasally (as 0.1mL/nostril). 2–8yrs: 1 or 2 doses/season (depends on vaccination history as per annual ACIP recommendation); if 2 doses, give at least 1 month apart. 9–49yrs: 1 dose/season.
Flumist Quadrivalent Contraindications
Contraindications
Allergy to egg protein, gentamicin, gelatin, or arginine. Life-threatening reaction to previous flu vaccine. Concomitant aspirin in patients 2–17yrs of age (Reye's syndrome).
Flumist Quadrivalent Boxed Warnings
Not Applicable
Flumist Quadrivalent Warnings/Precautions
Warnings/Precautions
Use current formulation only. Asthmatics or children <5yrs old with recurrent wheezing: may be at increased risk of wheezing following administration. Guillain-Barre syndrome within 6 weeks of previous flu vaccine. Underlying medical conditions predisposing to flu complications. Immunocompromised. Have epinephrine inj (1:1000) available. Pregnancy. Nursing mothers.
Flumist Quadrivalent Pharmacokinetics
See Literature
Flumist Quadrivalent Interactions
Interactions
Concomitant vaccines: see full labeling. Do not administer until 48hrs after antiviral therapy cessation. Do not give antivirals within 2 weeks of administration.
Flumist Quadrivalent Adverse Reactions
Adverse Reactions
Rhinorrhea/nasal congestion, fever, sore throat, decreased appetite, irritability; wheezing.
Flumist Quadrivalent Clinical Trials
See Literature
Flumist Quadrivalent Note
Not Applicable
Flumist Quadrivalent Patient Counseling
See Literature
