Flagyl Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
See Also
How Supplied
Manufacturer
Mechanism of Action
Flagyl Indications
Indications
Flagyl Dosage and Administration
Adult
Children
Flagyl Contraindications
Contraindications
Flagyl Boxed Warnings
Not Applicable
Flagyl Warnings/Precautions
Warnings/Precautions
Flagyl Pharmacokinetics
Absorption
-
Disposition of metronidazole in the body is similar for both oral and intravenous dosage forms.
-
Following oral administration, the peak plasma concentration is reached between 1 to 2 hours.
-
Plasma concentrations of oral metronidazole are proportional to the administered dose. Oral 250mg, 500mg, or 2000mg achieved peak plasma concentrations of 6 mcg/mL, 12 mcg/mL, and 40 mcg/mL, respectively.
Distribution
-
<20% is bound to plasma proteins.
-
Distributed in CSF, saliva, and breast milk at concentrations similar to those found in plasma.
Elimination
-
Renal (60% to 80% of the dose), fecal (6% to 15%).
-
Half-life: 8 hours.
Flagyl Interactions
Interactions
Flagyl Adverse Reactions
Adverse Reactions
Flagyl Clinical Trials
See Literature
Flagyl Note
Not Applicable
Flagyl Patient Counseling
Flagyl Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
See Also
How Supplied
Manufacturer
Mechanism of Action
Flagyl Indications
Indications
Flagyl Dosage and Administration
Adult
Children
Flagyl Contraindications
Contraindications
Flagyl Boxed Warnings
Not Applicable
Flagyl Warnings/Precautions
Warnings/Precautions
Flagyl Pharmacokinetics
Absorption
-
Disposition of metronidazole in the body is similar for both oral and intravenous dosage forms.
-
Following oral administration, the peak plasma concentration is reached between 1 to 2 hours.
-
Plasma concentrations of oral metronidazole are proportional to the administered dose. Oral 250mg, 500mg, or 2000mg achieved peak plasma concentrations of 6 mcg/mL, 12 mcg/mL, and 40 mcg/mL, respectively.
Distribution
-
<20% is bound to plasma proteins.
-
Distributed in CSF, saliva, and breast milk at concentrations similar to those found in plasma.
Elimination
-
Renal (60% to 80% of the dose), fecal (6% to 15%).
-
Half-life: 8 hours.
Flagyl Interactions
Interactions
Flagyl Adverse Reactions
Adverse Reactions
Flagyl Clinical Trials
See Literature
Flagyl Note
Not Applicable
Flagyl Patient Counseling
Flagyl Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
See Also
How Supplied
Manufacturer
Mechanism of Action
Flagyl Indications
Indications
Flagyl Dosage and Administration
Adult
Children
Flagyl Contraindications
Contraindications
Flagyl Boxed Warnings
Not Applicable
Flagyl Warnings/Precautions
Warnings/Precautions
Flagyl Pharmacokinetics
Absorption
-
Disposition of metronidazole in the body is similar for both oral and intravenous dosage forms.
-
Following oral administration, the peak plasma concentration is reached between 1 to 2 hours.
-
Plasma concentrations of oral metronidazole are proportional to the administered dose. Oral 250mg, 500mg, or 2000mg achieved peak plasma concentrations of 6 mcg/mL, 12 mcg/mL, and 40 mcg/mL, respectively.
Distribution
-
<20% is bound to plasma proteins.
-
Distributed in CSF, saliva, and breast milk at concentrations similar to those found in plasma.
Elimination
-
Renal (60% to 80% of the dose), fecal (6% to 15%).
-
Half-life: 8 hours.
Flagyl Interactions
Interactions
Flagyl Adverse Reactions
Adverse Reactions
Flagyl Clinical Trials
See Literature
Flagyl Note
Not Applicable