Firazyr Generic Name & Formulations
Icatibant 10mg/mL; soln for SC inj; preservative-free.
Bradykinin B2 receptor antagonist.
Single-use prefilled syringe (3mL)—1, 3
For acute attacks of hereditary angioedema (HAE).
Firazyr Dosage and Administration
≥18yrs: 30mg SC in abdominal area; may give additional doses at intervals of at least 6hrs if response inadequate or symptoms recur. Max 3 doses/24hrs.
<18yrs: not established.
Firazyr Boxed Warnings
Advise patients to seek medical attention after treating laryngeal attack given the potential for airway obstruction. Elderly. Labor & delivery. Pregnancy. Nursing mothers.
May attenuate the antihypertensive effect of ACE inhibitors.
Firazyr Adverse Reactions
Inj site reactions, pyrexia, transaminase increase, dizziness, rash.
Firazyr Clinical Trials
Firazyr Patient Counseling