Famotidine Injection

  • Hyperacidity, GERD, and ulcers

Famotidine Injection Generic Name & Formulations

General Description

Famotidine 10mg/mL; soln for IV inj or infusion after dilution; multidose vials contain benzyl alcohol.

Pharmacological Class

H2 blocker.

How Supplied

Tabs—30, 100; Susp—50mL; Inj—contact supplier

Famotidine Injection Indications


Hospitalized patients with pathological hypersecretory conditions, intractable ulcers, or as a short-term alternative to oral dosage forms.

Famotidine Injection Dosage and Administration


Give by IV inj over 2 mins or infuse over 15–30 mins. 20mg every 12hrs.


See full labeling. Give by IV inj over 2 mins or infuse over 15 mins. <1yr: not recommended. 1–16yrs: initially 0.25mg/kg every 12hrs; max 40mg/day.

Famotidine Injection Contraindications


History of serious hypersensitivity reactions to H2 receptor antagonists.

Famotidine Injection Boxed Warnings

Not Applicable

Famotidine Injection Warnings/Precautions


Symptomatic response does not preclude gastric malignancy; evaluate prior to initiation. Moderate to severe renal impairment (CrCl <50mL/min): reduce to ½ the dose or prolong dosing interval to 36–48hrs. Elderly: use low doses. Pregnancy. Nursing mothers.

Famotidine Injection Pharmacokinetics

See Literature

Famotidine Injection Interactions


Concomitant dasatinib, delavirdine mesylate, cefditoren, fosamprenavir: not recommended. May alter absorption of pH-dependent drugs (eg, atazanavir, erlotinib, ketoconazole, itraconazole, ledipasvir/sofosbuvir, nilotinib, rilpivirine). May potentiate CYP1A2 substrates (eg, tizanidine); avoid; if necessary, monitor for hypotension, bradycardia, drowsiness. May give antacids concomitantly.

Famotidine Injection Adverse Reactions

Adverse Reactions

Headache, dizziness, constipation, diarrhea, inj site reactions; rare: CNS reactions, prolonged QT interval in renal impairment (moderate and severe).

Famotidine Injection Clinical Trials

See Literature

Famotidine Injection Note


Formerly known under the brand name Pepcid Injection.

Famotidine Injection Patient Counseling

See Literature