Ergotamine Tartrate + Caffeine Suppositories Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Ergotamine Tartrate + Caffeine Suppositories Indications
Indications
Ergotamine Tartrate + Caffeine Suppositories Dosage and Administration
Adult
1 supp rectally at onset of attack, then 1 supp after 1 hour if needed; max 2 supps/attack, 5 supps/week.
Children
Other Modifications
There have been reports of drug abuse and psychological dependence in patients on ergotamine tartrate and caffeine therapy.
Ergotamine Tartrate + Caffeine Suppositories Contraindications
Contraindications
Peripheral vascular disease. Coronary heart disease. Hypertension. Hepatic or renal dysfunction. Sepsis. Concomitant potent CYP3A4 inhibitors (eg, ritonavir, nelfinavir, indinavir, erythromycin, clarithromycin, troleandomycin, ketoconazole, itraconazole) or other vasoconstrictors. Pregnancy. Labor and delivery.
Ergotamine Tartrate + Caffeine Suppositories Boxed Warnings
Boxed Warning
Peripheral ischemia following coadministration with strong CYP3A4 inhibitors.
Ergotamine Tartrate + Caffeine Suppositories Warnings/Precautions
Warnings/Precautions
Ergotamine Tartrate + Caffeine Suppositories Pharmacokinetics
Elimination
Ergotamine Tartrate + Caffeine Suppositories Interactions
Interactions
Ergotamine Tartrate + Caffeine Suppositories Adverse Reactions
Adverse Reactions
Ergotamine Tartrate + Caffeine Suppositories Clinical Trials
See Literature