Anesthetics:
Indications for Ephedrine Sulfate Injection:
As a pressor agent, particularly during spinal anesthesia when hypotension frequently occurs.
Adult:
25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.
Children:
0.5mg/kg by SC or IM every 4–6 hours.
Warnings/Precautions:
Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacologic Class:
Sympathomimetic.
Interactions:
MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.
Adverse Reactions:
Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.
How Supplied:
Contact supplier.
Asthma/COPD:
Indications for Ephedrine Sulfate Injection:
Treatment of allergic disorders, such as bronchial asthma.
Adult:
25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.
Children:
0.5mg/kg by SC or IM every 4–6 hours.
Warnings/Precautions:
Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacologic Class:
Sympathomimetic.
Interactions:
MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.
Adverse Reactions:
Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.
How Supplied:
Contact supplier.
Myasthenia gravis:
Indications for Ephedrine Sulfate Injection:
Myasthenia gravis.
Adult:
25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.
Children:
0.5mg/kg by SC or IM every 4–6 hours.
Warnings/Precautions:
Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacologic Class:
Sympathomimetic.
Interactions:
MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.
Adverse Reactions:
Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.
How Supplied:
Contact supplier.
Sleep-wake disorders:
Indications for Ephedrine Sulfate Injection:
As a CNS stimulant in narcolepsy and depressive states.
Adult:
25–50mg by SC or IM; or 5–25mg by slow IV, may be repeated in 5–10 minutes if necessary.
Children:
0.5mg/kg by SC or IM every 4–6 hours.
Warnings/Precautions:
Heart disease. Angina. Diabetes. Hyperthyroidism. Prostatic hypertrophy. Hypertension. Prolonged use may produce syndrome resembling anxiety. Tolerance may develop; discontinuing may restore effectiveness. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacologic Class:
Sympathomimetic.
Interactions:
MAOIs during or within 14 days: avoid. Concomitant general anesthetics (eg. cyclopropane, halogenated hydrocarbons), digitalis glycosides may cause cardiac arrhythmias. May inhibit hypotensive effect of guanethidine, bethanidine, debrisoquin. Severe hypotension with concomitant oxytocics.
Adverse Reactions:
Nervousness, insomnia, vertigo, headache, tachycardia, palpitation, sweating, GI upset, anorexia, vesical sphincter spasm, urinary retention, precordial pain, cardiac arrhythmias.
How Supplied:
Contact supplier.
