• Rhinitis/rhinorrhea (intranasal products)

Dymista Generic Name & Formulations

General Description

Azelastine HCl, fluticasone propionate 137mcg/50mcg; per 0.137mL metered nasal spray; aqueous suspension.

Pharmacological Class

Antihistamine + corticosteroid.

How Supplied

Pump (23g)—120 sprays


Generic Availability


Dymista Indications


Seasonal allergic rhinitis.

Dymista Dosage and Administration

Adults and Children

<6yrs: not established. ≥6yrs: 1 spray per nostril twice daily.

Dymista Contraindications

Not Applicable

Dymista Boxed Warnings

Not Applicable

Dymista Warnings/Precautions


Avoid use in recent nasal ulcers, nasal surgery, or nasal trauma. Respiratory tract tuberculosis. Infections (eg, fungal, bacterial, viral, ocular herpes simplex). Avoid exposure to chickenpox and measles; if exposed, consider anti-infective prophylactic therapy. If adrenal insufficiency exists following systemic corticosteroid therapy, replacement with topical corticosteroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude, depression). Monitor growth routinely in children. Monitor for hypercorticism and HPA axis suppression (if occur discontinue gradually), and Candida infection or other nasal mucosal changes. History of increased intraocular pressure, glaucoma, and/or cataracts; monitor any change in vision. Avoid eyes. Pregnancy. Nursing mothers: monitor infants.

Dymista Pharmacokinetics

See Literature

Dymista Interactions


Avoid alcohol or other CNS depressants. Concomitant ritonavir: not recommended. Caution with other potent CYP3A4 inhibitors (eg, ketoconazole).

Dymista Adverse Reactions

Adverse Reactions

Dysgeusia, epistaxis, headache; somnolence, vision changes.

Dymista Clinical Trials

See Literature

Dymista Note

Not Applicable

Dymista Patient Counseling

See Literature