Donnatal Tablets

  • Hyperacidity, GERD, and ulcers

Donnatal Tablets Generic Name & Formulations

General Description

Phenobarbital 16.2mg, hyoscyamine sulfate 0.1037mg, atropine sulfate 0.0194mg, scopolamine HBr 0.0065mg.

Pharmacological Class

Barbiturate + anticholinergics.

See Also

How Supplied

Tabs—100, 1000; Elixir—4oz, pt

Donnatal Tablets Indications


Adjunct in irritable bowel syndrome, enterocolitis, duodenal ulcer.

Donnatal Tablets Dosage and Administration


1–2 tabs 3–4 times daily.


Not recommended.

Donnatal Tablets Contraindications


Glaucoma. Porphyria. Unstable cardiovascular status. GI or GU obstruction. Paralytic ileus or intestinal atony. Toxic megacolon. Severe ulcerative colitis. Myasthenia gravis. Hiatal hernia. History of paradoxical reactions to phenobarbital.

Donnatal Tablets Boxed Warnings

Not Applicable

Donnatal Tablets Warnings/Precautions


Renal or hepatic impairment. Autonomic neuropathy. Cardiovascular disease. Hypertension. Hyperthyroidism. Drug abusers. High environmental temperature. Gastric ulcer. Diarrhea. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers.

Donnatal Tablets Pharmacokinetics

See Literature

Donnatal Tablets Interactions


Potentiated CNS depression with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics, narcotics, type I antiarrhythmics, antihistamines, phenothiazines, tricyclics. May antagonize anticoagulants, CYP450 substrates.

Donnatal Tablets Adverse Reactions

Adverse Reactions

Drowsiness, anticholinergic effects, paradoxical excitement.

Donnatal Tablets Clinical Trials

See Literature

Donnatal Tablets Note

Not Applicable

Donnatal Tablets Patient Counseling

See Literature