Ditropan Xl

  • Overactive bladder/enuresis

Ditropan Xl Generic Name & Formulations

General Description

Oxybutynin chloride 5mg, 10mg; ext-rel tabs.

Pharmacological Class


How Supplied


Generic Availability


Ditropan Xl Indications


Overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency. Neurologic detrusor overactivity symptoms in children.

Ditropan Xl Dosage and Administration


Swallow whole. Take with fluid. Initially 5mg or 10mg once daily; may increase weekly in 5mg increments; max 30mg/day.


<6yrs: not recommended. ≥6yrs: Swallow whole. Take with fluid. Initially 5mg once daily; may increase in 5mg increments; max 20mg/day.

Ditropan Xl Contraindications


Urinary or gastric retention. Other severe decreased GI motility conditions. Uncontrolled narrow-angle glaucoma.

Ditropan Xl Boxed Warnings

Not Applicable

Ditropan Xl Warnings/Precautions


Discontinue if angioedema develops. Monitor for anticholinergic CNS effects (esp. in the first few months after initiation or dose increases); consider dose reduction or discontinuation if occur. Bladder outflow or GI obstruction. Ulcerative colitis. Intestinal atony. GERD. GI narrowing or stricture. Pre-existing dementia. Parkinson's disease. Myasthenia gravis. Decreased GI motility in those with autonomic neuropathy. Exposure to high environmental temperatures. Hepatic or renal impairment. Pregnancy. Nursing mothers.

Ditropan Xl Pharmacokinetics

See Literature

Ditropan Xl Interactions


Increased drowsiness with alcohol, other CNS depressants. Additive anticholinergic effects with other anticholinergics. May be potentiated by CYP3A4 inhibitors (eg, ketoconazole, itraconazole, miconazole, erythromycin, clarithromycin). Decreases GI motility, possibly affecting absorption of other drugs. Caution with drugs that can cause or exacerbate esophagitis (eg, bisphosphonates).

Ditropan Xl Adverse Reactions

Adverse Reactions

Dry mouth, constipation, diarrhea, somnolence, headache, dizziness, nausea, tachycardia, blurred vision, dry eyes, other anticholinergic effects.

Ditropan Xl Clinical Trials

See Literature

Ditropan Xl Note

Not Applicable

Ditropan Xl Patient Counseling

See Literature