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Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Generic Name & Formulations
Legal Class
Rx
General Description
Tetanus and diphtheria toxoids; aluminum adsorbed; susp for IM inj; multi-dose vial preserved with thimerosal, single-dose vials contain trace amounts of thimerosal.
Pharmacological Class
DT vaccine.
How Supplied
Single-dose vials—10
Multi-dose vial (5mL)—1
Multi-dose vial (5mL)—1
Manufacturer
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Indications
Indications
Tetanus and diphtheria immunization in patients 6 weeks to 7yrs of age when pertussis vaccine cannot be used.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Dosage and Administration
Children
<6wks and ≥7yrs: not recommended. Give IM in anterolateral thigh or deltoid. 6wks–1yr: three 0.5mL doses 4–8 weeks apart, then 4th dose 6–12 months after third dose. 1–6yrs (up to 7yrs): two 0.5mL doses 4–8 weeks apart, then 3rd dose 6–12 months after the second dose (if >7yrs, use Td vaccine). Booster dose: see literature.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Contraindications
Contraindications
History of systemic allergic or neurologic reactions to a previous dose of DT.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Boxed Warnings
Not Applicable
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Warnings/Precautions
Warnings/Precautions
Defer in moderate or severe active respiratory or other febrile infection (may vaccinate if mild or minor illness) or during polio outbreak. Bleeding disorders. Immunosuppressed. Have epinephrine (1:1000) available.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Pharmacokinetics
See Literature
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Interactions
Interactions
May get suboptimal response with immunosuppressants (eg, chemotherapy, high dose corticosteroids ≥2 weeks, radiation); consider deferring.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Adverse Reactions
Adverse Reactions
Local reactions (eg, erythema, edema), malaise, fever, hypotension, arthralgia, nausea; rare: neurologic disorders.
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Clinical Trials
See Literature
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Note
Not Applicable
Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Patient Counseling
See Literature
