Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use)

— THERAPEUTIC DISORDERS TREATED —
  • Vaccines

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Generic Name & Formulations

General Description

Tetanus and diphtheria toxoids; aluminum adsorbed; susp for IM inj; multi-dose vial preserved with thimerosal, single-dose vials contain trace amounts of thimerosal.

Pharmacological Class

DT vaccine.

How Supplied

Single-dose vials—10
Multi-dose vial (5mL)—1

Manufacturer

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Indications

Indications

Tetanus and diphtheria immunization in patients 6 weeks to 7yrs of age when pertussis vaccine cannot be used.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Dosage and Administration

Children

<6wks and ≥7yrs: not recommended. Give IM in anterolateral thigh or deltoid. 6wks–1yr: three 0.5mL doses 4–8 weeks apart, then 4th dose 6–12 months after third dose. 1–6yrs (up to 7yrs): two 0.5mL doses 4–8 weeks apart, then 3rd dose 6–12 months after the second dose (if >7yrs, use Td vaccine). Booster dose: see literature.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Contraindications

Contraindications

History of systemic allergic or neurologic reactions to a previous dose of DT.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Boxed Warnings

Not Applicable

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Warnings/Precautions

Warnings/Precautions

Defer in moderate or severe active respiratory or other febrile infection (may vaccinate if mild or minor illness) or during polio outbreak. Bleeding disorders. Immunosuppressed. Have epinephrine (1:1000) available.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Pharmacokinetics

See Literature

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Interactions

Interactions

May get suboptimal response with immunosuppressants (eg, chemotherapy, high dose corticosteroids ≥2 weeks, radiation); consider deferring.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Adverse Reactions

Adverse Reactions

Local reactions (eg, erythema, edema), malaise, fever, hypotension, arthralgia, nausea; rare: neurologic disorders.

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Clinical Trials

See Literature

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Note

Not Applicable

Diphtheria And Tetanus Toxoids Adsorbed (for Pediatric Use) Patient Counseling

See Literature