• Poisoning/overdose

Digifab Generic Name & Formulations

General Description

Digoxin Immune Fab (ovine) 40mg/vial; IV inj after reconstitution; preservative-free.

Pharmacological Class

Digoxin binder.

How Supplied

Single-use vial—1


Digifab Indications


Digoxin toxicity or overdose.

Digifab Dosage and Administration

Adults and Children

See literature. Dose based on amount of digoxin or digitoxin to be neutralized. Contents of 1 vial neutralizes 0.5mg digoxin.

Digifab Contraindications

Not Applicable

Digifab Boxed Warnings

Not Applicable

Digifab Warnings/Precautions


Previous allergies to antibiotics, sheep antibodies, papain or papaya extracts. Monitor potassium, renal, and cardiac function. Postpone redigitalization until Fab fragments cleared. Interferes with digitalis immunoassays. Pregnancy (Cat.C). Nursing mothers.

Digifab Pharmacokinetics

See Literature

Digifab Interactions

Digifab Adverse Reactions

Adverse Reactions

Symptoms of digoxin withdrawal. Hypokalemia.

Digifab Clinical Trials

See Literature

Digifab Note

Not Applicable

Digifab Patient Counseling

See Literature