Diflucan Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Generic Availability
Diflucan Indications
Indications
Diflucan Dosage and Administration
Adult
Children
Diflucan Contraindications
Contraindications
Diflucan Boxed Warnings
Not Applicable
Diflucan Warnings/Precautions
Warnings/Precautions
Diflucan Pharmacokinetics
Elimination
Diflucan Interactions
Interactions
See Contraindications. Avoid concomitant voriconazole; if needed, monitor closely esp. when given within 24hrs after fluconazole. Caution with amiodarone (esp. with high-dose fluconazole), other drugs metabolized by CYP2C9 and CYP3A4 with a narrow therapeutic window. Potentiates abrocitinib, lemborexant; avoid. Potentiates ivacaftor, warfarin, sulfonylureas, oral midazolam, theophylline, tofacitinib, tolvaptan, triazolam, alfentanil, amitriptyline, nortriptyline, saquinavir, sirolimus, carbamazepine, NSAIDs, zidovudine; monitor and adjust dose as necessary. May increase levels of phenytoin, halofantrine, ibrutinib, methadone, rifabutin, tacrolimus, vinca alkaloids, cyclosporine, fentanyl, CCBs, losartan, lurasidone; monitor. Concomitant celecoxib: reduce celecoxib dose by half. Increased risk of myopathy/rhabdomyolysis with concomitant HMG-CoA reductase inhibitors; may need dose reduction of these statins. Avoid concomitant olaparib; reduce its dose if unavoidable. May be potentiated by diuretics. May be antagonized by oral cimetidine, rifampin. Concomitant prednisone: monitor for adrenal cortex insufficiency when fluconazole stopped. CNS effects with Vitamin A. Oral contraceptives: see full labeling. Avoid other hepatotoxic drugs.
Diflucan Adverse Reactions
Adverse Reactions
Diflucan Clinical Trials
See Literature
Diflucan Note
Not Applicable
Diflucan Patient Counseling
See Literature