Differin Gel

  • Acne

Differin Gel Generic Name & Formulations

General Description

Adapalene 0.3%; alcohol-free.

Pharmacological Class


How Supplied

Gel, crm—45g; Lotion—2oz

Differin Gel Indications


Acne vulgaris.

Differin Gel Dosage and Administration


Apply thin film to affected areas once daily after washing. Reduce frequency or discontinue if prolonged or severe irritation occurs.


Not established.

Differin Gel Contraindications

Not Applicable

Differin Gel Boxed Warnings

Not Applicable

Differin Gel Warnings/Precautions


Discontinue if allergic or anaphylactic reactions occur. Do not use on cuts, abrasions, broken, eczematous, or sunburned skin. Avoid eyes, lips, angles of the nose, mucous membranes, sun, UV light. Increased irritation in extreme weather. Pregnancy. Nursing mothers: avoid areas with increased risk for potential ingestion or ocular exposure to infant.

Differin Gel Pharmacokinetics

See Literature

Differin Gel Interactions


Avoid use until the effects of sulfur, resorcinol, or salicylic acid have subsided. Avoid waxing treated areas. Caution with other photosensitizers or irritants.

Differin Gel Adverse Reactions

Adverse Reactions

Erythema, scaling, dryness, pruritus, burning, stinging.

Differin Gel Clinical Trials

See Literature

Differin Gel Note

Not Applicable

Differin Gel Patient Counseling

See Literature