Differin Cream

  • Acne

Differin Cream Generic Name & Formulations

General Description

Adapalene 0.1%; alcohol-free.

Pharmacological Class


How Supplied

Gel, crm—45g; Lotion—2oz

Differin Cream Indications


Acne vulgaris.

Differin Cream Dosage and Administration


Apply thin film to affected areas once daily after washing. Reduce frequency or discontinue if prolonged or severe irritation occurs.


Not established.

Differin Cream Contraindications

Not Applicable

Differin Cream Boxed Warnings

Not Applicable

Differin Cream Warnings/Precautions


Discontinue if allergic or anaphylactic reactions occur. Do not use on cuts, abrasions, broken, eczematous, or sunburned skin. Avoid eyes, lips, angles of the nose, mucous membranes, sun, UV light. Increased irritation in extreme weather. Pregnancy. Nursing mothers: avoid areas with increased risk for potential ingestion or ocular exposure to infant.

Differin Cream Pharmacokinetics

See Literature

Differin Cream Interactions


Avoid use until the effects of sulfur, resorcinol, or salicylic acid have subsided. Avoid waxing treated areas. Caution with other photosensitizers or irritants.

Differin Cream Adverse Reactions

Adverse Reactions

Erythema, scaling, dryness, pruritus, burning, stinging.

Differin Cream Clinical Trials

See Literature

Differin Cream Note

Not Applicable

Differin Cream Patient Counseling

See Literature