Diethylpropion Generic Name & Formulations
Legal Class
General Description
Pharmacological Class
How Supplied
Manufacturer
Diethylpropion Indications
Indications
For the management of exogenous obesity as a short-term adjunct (a few weeks) in a regimen of weight reduction based on caloric restriction in patients with an initial body mass index (BMI) of 30 kg/m2 or higher and who have not responded to appropriate weight reducing regimen (diet and/or exercise) alone. Indicated for use as monotherapy only.
Diethylpropion Dosage and Administration
Adult
25mg 3 times daily, 1 hr before meals, and in midevening for night hunger or one 75mg sustained-release tab daily in midmorning.
Children
Renal Impairment
Diethylpropion is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function.
Diethylpropion Contraindications
Contraindications
Diethylpropion Boxed Warnings
Not Applicable
Diethylpropion Warnings/Precautions
Warnings/Precautions
Diethylpropion Pharmacokinetics
Absorption
Rapidly absorbed from the GI tract after oral administration.
Elimination
Diethylpropion and its metabolites are excreted mainly by the kidney. Plasma half-life of the aminoketone metabolites is estimated to be between 4 to 6 hours.