• Bacterial infections

Dicloxacillin Generic Name & Formulations

General Description

Dicloxacillin sodium 250mg, 500mg; caps.

Pharmacological Class

Penicillinase-resistant penicillin.

How Supplied

Contact supplier.

Dicloxacillin Indications


Susceptible infections caused by penicillinase-producing staphylococci. Not for initial therapy in serious, life-threatening infections.

Dicloxacillin Dosage and Administration


Take on an empty stomach. ≥40kg: Mild to moderate infections: 125mg every 6hrs. Severe infections: 250mg every 6hrs.


Take on an empty stomach. <40kg: Mild to moderate infections: 12.5mg/kg/day in divided doses every 6hrs. Severe: 25mg/kg/day in divided doses every 6hrs.

Dicloxacillin Contraindications

Not Applicable

Dicloxacillin Boxed Warnings

Not Applicable

Dicloxacillin Warnings/Precautions


Signficant allergy/asthma. Monitor blood, renal, and hepatic function in long-term use. Labor & delivery. Pregnancy (Cat.B). Nursing mothers.

Dicloxacillin Pharmacokinetics

See Literature

Dicloxacillin Interactions


Avoid concomitant tetracyclines, aminoglycosides. Serum levels increased by probenecid. May reduce anticoagulant response: monitor PT.

Dicloxacillin Adverse Reactions

Adverse Reactions

GI upset, hypersensitivity reactions, neurotoxic reactions, blood dyscrasias; C. difficile associated diarrhea.

Dicloxacillin Clinical Trials

See Literature

Dicloxacillin Note

Not Applicable

Dicloxacillin Patient Counseling

See Literature