Select therapeutic use:

Anxiety/OCD:

Indications for Diazepam Intensol:

Anxiety.

Adult Dosage:

Intensol: Mix with liquid or semi-solid food. 2–10mg 2–4 times daily. Elderly, debilitated: initially 2–2.5mg 1–2 times daily; increase gradually.

Children Dosage:

Intensol: mix with liquid or semi-solid food. <6months: see Contraindications. >6months: 1–2.5mg 3–4 times daily; increase gradually.

Diazepam Intensol Contraindications:

Children <6months. Myasthenia gravis. Severe respiratory insufficiency. Severe hepatic insufficiency. Sleep apnea syndrome. Acute narrow-angle glaucoma. Untreated open angle glaucoma.

Diazepam Intensol Warnings/Precautions:

Increased risk of drug-related mortality from concomitant use with opioids. Monitor for CNS depressant effects. Discontinue if paradoxical reaction occurs. Respiratory insufficiency. Depression. Suicidal tendencies. Drug or alcohol abuse. May increase severity of seizures. Renal or hepatic impairment. Avoid abrupt cessation. Reevaluate periodically. Monitor blood counts, liver function. Elderly. Debilitated. Labor & delivery. Psychosis, pregnancy, nursing mothers: not recommended.

Diazepam Intensol Classification:

Benzodiazepine.

Diazepam Intensol Interactions:

Increased sedation, respiratory depression, coma, and death with concomitant opioids; reserve use in those for whom alternative treatment options are inadequate; if needed, limit dosages/durations to minimum and monitor. Potentiates CNS depression with alcohol, other CNS depressants (eg, phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, antihistamines, barbiturates, MAOIs, other antidepressants). Potentiated by CYP3A or CYP2C19 inhibitors (eg, cimetidine, fluoxetine, fluvoxamine, ketoconazole, omeprazole). May affect or be affected by phenytoin.

Adverse Reactions:

Drowsiness, fatigue, muscle weakness, ataxia, CNS effects, GI disturbances, hypotension, salivation changes, neutropenia, jaundice; paradoxical excitement.

How Supplied:

Soln—500mL; Intensol—30mL (w. dropper)

Muscle spasms:

Indications for Diazepam Intensol:

Adjunct for skeletal muscle spasm.

Adult Dosage:

Intensol: Mix with liquid or semi-solid food. 2–10mg 3–4 times daily. Elderly, debilitated: initially 2–2.5mg 1–2 times daily; increase gradually.

Children Dosage:

Intensol: mix with liquid or semi-solid food. <6months: see Contraindications. >6months: 1–2.5mg 3–4 times daily; increase gradually.

Diazepam Intensol Contraindications:

Children <6months. Myasthenia gravis. Severe respiratory insufficiency. Severe hepatic insufficiency. Sleep apnea syndrome. Acute narrow-angle glaucoma. Untreated open angle glaucoma.

Diazepam Intensol Warnings/Precautions:

Increased risk of drug-related mortality from concomitant use with opioids. Monitor for CNS depressant effects. Discontinue if paradoxical reaction occurs. Respiratory insufficiency. Depression. Suicidal tendencies. Drug or alcohol abuse. May increase severity of seizures. Renal or hepatic impairment. Avoid abrupt cessation. Reevaluate periodically. Monitor blood counts, liver function. Elderly. Debilitated. Labor & delivery. Psychosis, pregnancy, nursing mothers: not recommended.

Diazepam Intensol Classification:

Benzodiazepine.

Diazepam Intensol Interactions:

Increased sedation, respiratory depression, coma, and death with concomitant opioids; reserve use in those for whom alternative treatment options are inadequate; if needed, limit dosages/durations to minimum and monitor. Potentiates CNS depression with alcohol, other CNS depressants (eg, phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, antihistamines, barbiturates, MAOIs, other antidepressants). Potentiated by CYP3A or CYP2C19 inhibitors (eg, cimetidine, fluoxetine, fluvoxamine, ketoconazole, omeprazole). May affect or be affected by phenytoin.

Adverse Reactions:

Drowsiness, fatigue, muscle weakness, ataxia, CNS effects, GI disturbances, hypotension, salivation changes, neutropenia, jaundice; paradoxical excitement.

How Supplied:

Soln—500mL; Intensol—30mL (w. dropper)

Seizure disorders:

Indications for Diazepam Intensol:

Adjunct in convulsive disorders.

Adult Dosage:

Intensol: Mix with liquid or semi-solid food. 2–10mg 2–4 times daily. Elderly, debilitated: initially 2–2.5mg 1–2 times daily; increase gradually.

Children Dosage:

Intensol: mix with liquid or semi-solid food. <6months: see Contraindications. >6months: 1–2.5mg 3–4 times daily; increase gradually.

Diazepam Intensol Contraindications:

Children <6months. Myasthenia gravis. Severe respiratory insufficiency. Severe hepatic insufficiency. Sleep apnea syndrome. Acute narrow-angle glaucoma. Untreated open angle glaucoma.

Diazepam Intensol Warnings/Precautions:

Increased risk of drug-related mortality from concomitant use with opioids. Monitor for CNS depressant effects. Discontinue if paradoxical reaction occurs. Respiratory insufficiency. Depression. Suicidal tendencies. Drug or alcohol abuse. May increase severity of seizures. Renal or hepatic impairment. Avoid abrupt cessation. Reevaluate periodically. Monitor blood counts, liver function. Elderly. Debilitated. Labor & delivery. Psychosis, pregnancy, nursing mothers: not recommended.

Diazepam Intensol Classification:

Benzodiazepine.

Diazepam Intensol Interactions:

Increased sedation, respiratory depression, coma, and death with concomitant opioids; reserve use in those for whom alternative treatment options are inadequate; if needed, limit dosages/durations to minimum and monitor. Potentiates CNS depression with alcohol, other CNS depressants (eg, phenothiazines, antipsychotics, anxiolytics/sedatives, hypnotics, anticonvulsants, narcotic analgesics, anesthetics, antihistamines, barbiturates, MAOIs, other antidepressants). Potentiated by CYP3A or CYP2C19 inhibitors (eg, cimetidine, fluoxetine, fluvoxamine, ketoconazole, omeprazole). May affect or be affected by phenytoin.

Adverse Reactions:

Drowsiness, fatigue, muscle weakness, ataxia, CNS effects, GI disturbances, hypotension, salivation changes, neutropenia, jaundice; paradoxical excitement.

How Supplied:

Soln—500mL; Intensol—30mL (w. dropper)