Bacterial infections:
Indications for DALVANCE:
Susceptible acute bacterial skin and skin structure infections (ABSSSI).
Adult Dosage:
Give by IV infusion over 30 mins. CrCl ≥30mL/min or on regular hemodialysis: administer 1500mg as single dose, or 1000mg followed by 500mg one week later. Renal impairment (CrCl <30mL/min) and who are not receiving regularly scheduled hemodialysis: administer 1125mg as single dose, or 750mg followed by 375mg one week later.
Children Dosage:
Not established.
DALVANCE Warnings/Precautions:
History of glycopeptide allergy. Discontinue if serious hypersensitivity or skin reactions occur. Moderate or severe hepatic impairment (Child-Pugh Class B or C). Renal impairment (CrCl <30mL/min). Pregnancy (Cat.C). Nursing mothers.
DALVANCE Classification:
Lipoglycopeptide.
Adverse Reactions:
Nausea, headache, diarrhea, vomiting, rash, pruritus; ALT elevations, infusion-related reactions (eg, Red-Man Syndrome), C. difficile-associated diarrhea (discontinue if occurs).
Generic Drug Availability:
NO
How Supplied:
Single-use vial—1
