Cyclobenzaprine Hcl Tablets Generic Name & Formulations
Cyclobenzaprine HCl 5mg, 7.5mg, 10mg; tabs.
Muscle relaxant (central).
Cyclobenzaprine Hcl Tablets Indications
Relief of acute muscle spasm, as adjunct to rest and physical therapy.
Cyclobenzaprine Hcl Tablets Dosage and Administration
≥15yrs: initially 5mg 3 times daily, may increase to 10mg 3 times daily; max 2–3 weeks. Elderly or mild hepatic impairment: initially 5mg and then titrate slowly upward.
<15yrs: not established.
Cyclobenzaprine Hcl Tablets Contraindications
Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.
Cyclobenzaprine Hcl Tablets Boxed Warnings
Cyclobenzaprine Hcl Tablets Warnings/Precautions
Moderate-to-severe hepatic impairment: not recommended. Urinary retention. Glaucoma. Increased intraocular pressure. Elderly. Pregnancy (Cat.B). Nursing mothers.
Cyclobenzaprine Hcl Tablets Pharmacokinetics
Cyclobenzaprine Hcl Tablets Interactions
See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, or MAOIs); monitor closely. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. Tramadol increases seizure risk.
Cyclobenzaprine Hcl Tablets Adverse Reactions
Drowsiness, dry mouth, dizziness, fatigue, headache, GI upset, asthenia, irritability, nervousness, blurred vision, confusion, arrhythmias, tachycardia, hypotension.
Cyclobenzaprine Hcl Tablets Clinical Trials
Cyclobenzaprine Hcl Tablets Note
Formerly known under the brand names Flexeril, Fexmid.
Cyclobenzaprine Hcl Tablets Patient Counseling