Cyclobenzaprine Hcl Tablets

— THERAPEUTIC DISORDERS TREATED —
  • Muscle spasms

Cyclobenzaprine Hcl Tablets Generic Name & Formulations

General Description

Cyclobenzaprine HCl 5mg, 7.5mg, 10mg; tabs.

Pharmacological Class

Muscle relaxant (central).

How Supplied

Contact supplier.

Cyclobenzaprine Hcl Tablets Indications

Indications

Relief of acute muscle spasm, as adjunct to rest and physical therapy.

Cyclobenzaprine Hcl Tablets Dosage and Administration

Adult

≥15yrs: initially 5mg 3 times daily, may increase to 10mg 3 times daily; max 2–3 weeks. Elderly or mild hepatic impairment: initially 5mg and then titrate slowly upward.

Children

<15yrs: not established.

Cyclobenzaprine Hcl Tablets Contraindications

Contraindications

Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.

Cyclobenzaprine Hcl Tablets Boxed Warnings

Not Applicable

Cyclobenzaprine Hcl Tablets Warnings/Precautions

Warnings/Precautions

Moderate-to-severe hepatic impairment: not recommended. Urinary retention. Glaucoma. Increased intraocular pressure. Elderly. Pregnancy (Cat.B). Nursing mothers.

Cyclobenzaprine Hcl Tablets Pharmacokinetics

See Literature

Cyclobenzaprine Hcl Tablets Interactions

Interactions

See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, or MAOIs); monitor closely. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. Tramadol increases seizure risk.

Cyclobenzaprine Hcl Tablets Adverse Reactions

Adverse Reactions

Drowsiness, dry mouth, dizziness, fatigue, headache, GI upset, asthenia, irritability, nervousness, blurred vision, confusion, arrhythmias, tachycardia, hypotension.

Cyclobenzaprine Hcl Tablets Clinical Trials

See Literature

Cyclobenzaprine Hcl Tablets Note

Notes

Formerly known under the brand names Flexeril, Fexmid.

Cyclobenzaprine Hcl Tablets Patient Counseling

See Literature