Lung surfactants/mucolytics:
Indications for CUROSURF:
Treatment ("rescue") of respiratory distress syndrome (RDS) in premature infants.
Adult:
Not applicable.
Children:
See literature. Give by intratracheal administration through an endotracheal tube. Each dose should be administered as 2 aliquots. Inital dose of 2.5mL/kg birth weight; may give 2 more doses of 1.25mL/kg birth weight at 12-hour intervals.
Warnings/Precautions:
Interrupt dosing if reflux of product into endotracheal tube, cyanosis, bradycardia, airway obstruction, hypoventilation, or endotracheal tube dislodgement occurs; treat; resume after stabilization. Monitor respiratory status and clinical condition frequently and carefully.
Pharmacologic Class:
Lung surfactant.
Adverse Reactions:
Bradycardia, hypotension, reflux of surfactant into endotracheal tube, others.
How Supplied:
Single-use vials (1.5mL, 3mL)—1
