• Skin infections (topicals)

Cortisporin Generic Name & Formulations

General Description

Hydrocortisone acetate 0.5%, polymyxin B (as sulfate) 10000 Units/g, neomycin (as sulfate) 0.35%; crm.

Pharmacological Class

Steroid + antibiotics.

How Supplied

Crm—7.5g; Oint—½oz


Cortisporin Indications


Short-term use in corticosteroid-responsive dermatoses with secondary infection.

Cortisporin Dosage and Administration


Apply sparingly and massage in 2–4 times daily.


Not recommended.

Cortisporin Contraindications


Do not use in eyes, external ear canal if eardrum perforated. Tuberculous, fungal, or viral lesions.

Cortisporin Boxed Warnings

Not Applicable

Cortisporin Warnings/Precautions


Intertrigo, diaper or stasis dermatitis or ulceration, extensive burns (neomycin may be absorbed). Avoid prolonged use or on large areas. Use lowest effective dose. Monitor for HPA axis suppression; avoid abrupt cessation if used for chronic conditions. Discontinue if infection persists or worsens or if superinfection occurs. Occlusion: not recommended. Pregnancy (Cat.C). Nursing mothers.

Cortisporin Pharmacokinetics

See Literature

Cortisporin Interactions

Cortisporin Adverse Reactions

Adverse Reactions

Local irritation, folliculitis, hypertrichosis, dermatitis, sensitization, ototoxicity, nephrotoxicity (if neomycin is significantly absorbed), HPA axis suppression (esp. in children), epidermal and dermal atrophy (esp. in thin-skinned or occluded areas).

Cortisporin Clinical Trials

See Literature

Cortisporin Note

Not Applicable

Cortisporin Patient Counseling

See Literature