Cortisporin Ointment

  • Skin infections (topicals)

Cortisporin Ointment Generic Name & Formulations

General Description

Hydrocortisone 1%, polymyxin B (as sulfate) 5000 Units/g, neomycin (as sulfate) 0.35%, bacitracin (as zinc) 400 Units/g.

Pharmacological Class

Steroid + antibiotics.

See Also

How Supplied

Crm—7.5g; Oint—½oz


Cortisporin Ointment Indications


Short-term use in corticosteroid-responsive dermatoses with secondary infection.

Cortisporin Ointment Dosage and Administration


Apply sparingly and massage in 2–4 times daily.


Not recommended.

Cortisporin Ointment Contraindications


Do not use in eyes, external ear canal if eardrum perforated. Tuberculous, fungal, or viral lesions.

Cortisporin Ointment Boxed Warnings

Not Applicable

Cortisporin Ointment Warnings/Precautions


Intertrigo, diaper or stasis dermatitis or ulceration, extensive burns (neomycin may be absorbed). Avoid prolonged use or on large areas. Use lowest effective dose. Monitor for HPA axis suppression; avoid abrupt cessation if used for chronic conditions. Discontinue if infection persists or worsens or if superinfection occurs. Occlusion: not recommended. Pregnancy (Cat.C). Nursing mothers.

Cortisporin Ointment Pharmacokinetics

See Literature

Cortisporin Ointment Interactions

Cortisporin Ointment Adverse Reactions

Adverse Reactions

Local irritation, folliculitis, hypertrichosis, dermatitis, sensitization, ototoxicity, nephrotoxicity (if neomycin is significantly absorbed), HPA axis suppression (esp. in children), epidermal and dermal atrophy (esp. in thin-skinned or occluded areas).

Cortisporin Ointment Clinical Trials

See Literature

Cortisporin Ointment Note

Not Applicable

Cortisporin Ointment Patient Counseling

See Literature