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Cortifoam Generic Name & Formulations
Legal Class
Rx
General Description
Hydrocortisone acetate 10%; aerosol foam.
Pharmacological Class
Steroid.
How Supplied
Aerosol—15g (w. applicator)
Manufacturer
Cortifoam Indications
Indications
Adjunct in ulcerative proctitis in patients who cannot retain steroid enemas.
Cortifoam Dosage and Administration
Adult
1 applicatorful rectally (80mg hydrocortisone) 1–2 times daily for 2–3 weeks. Then every other day. Discontinue if no improvement within 2–3 weeks.
Children
Not recommended.
Cortifoam Contraindications
Contraindications
Rectal obstruction. Abscess. Perforation. Peritonitis. Fresh intestinal anastomoses. Extensive fistulas and sinus tracts. Tuberculosis. Ocular herpes simplex. Psychosis. Peptic ulcer. Glomerulonephritis. Myasthenia gravis. Osteoporosis. Diverticulitis. Thrombophlebitis. Diabetes. Hyperthyroidism. Acute coronary disease. Hypertension. Limited cardiac reserve. Infections.
Cortifoam Boxed Warnings
Not Applicable
Cortifoam Warnings/Precautions
Warnings/Precautions
Postileorectostomy: not recommended. Exposure to varicella or vaccinia. Severe ulcerative disease. CHF. Renal or hepatic dysfunction. Monitor adrenal function and serum electrolytes. Avoid abrupt cessation. Vaccinations. Pregnancy (Cat.C). Nursing mothers.
Cortifoam Pharmacokinetics
See Literature
Cortifoam Interactions
Interactions
May antagonize insulin or oral hypoglycemics, anticoagulants, aspirin. Hypokalemia with amphotericin B or diuretics. May be potentiated by macrolides, cyclosporine.
Cortifoam Adverse Reactions
Adverse Reactions
Hypertension, fluid retention, hypokalemia, adrenal suppression, cataracts, glaucoma, psychosis, dysmenorrhea, myopathy, neuropathy, thrombophlebitis, peptic ulcer, impaired wound healing, convulsions, local irritation (folliculitis, hypertrichosis, acne, hypopigmentation, macerations, dermal and epidermal atrophy, secondary infections, striae, miliaria).
Cortifoam Clinical Trials
See Literature
Cortifoam Note
Not Applicable
Cortifoam Patient Counseling
See Literature
