• Colorectal disorders

Cortifoam Generic Name & Formulations

General Description

Hydrocortisone acetate 10%; aerosol foam.

Pharmacological Class


How Supplied

Aerosol—15g (w. applicator)


Cortifoam Indications


Adjunct in ulcerative proctitis in patients who cannot retain steroid enemas.

Cortifoam Dosage and Administration


1 applicatorful rectally (80mg hydrocortisone) 1–2 times daily for 2–3 weeks. Then every other day. Discontinue if no improvement within 2–3 weeks.


Not recommended.

Cortifoam Contraindications


Rectal obstruction. Abscess. Perforation. Peritonitis. Fresh intestinal anastomoses. Extensive fistulas and sinus tracts. Tuberculosis. Ocular herpes simplex. Psychosis. Peptic ulcer. Glomerulonephritis. Myasthenia gravis. Osteoporosis. Diverticulitis. Thrombophlebitis. Diabetes. Hyperthyroidism. Acute coronary disease. Hypertension. Limited cardiac reserve. Infections.

Cortifoam Boxed Warnings

Not Applicable

Cortifoam Warnings/Precautions


Postileorectostomy: not recommended. Exposure to varicella or vaccinia. Severe ulcerative disease. CHF. Renal or hepatic dysfunction. Monitor adrenal function and serum electrolytes. Avoid abrupt cessation. Vaccinations. Pregnancy (Cat.C). Nursing mothers.

Cortifoam Pharmacokinetics

See Literature

Cortifoam Interactions


May antagonize insulin or oral hypoglycemics, anticoagulants, aspirin. Hypokalemia with amphotericin B or diuretics. May be potentiated by macrolides, cyclosporine.

Cortifoam Adverse Reactions

Adverse Reactions

Hypertension, fluid retention, hypokalemia, adrenal suppression, cataracts, glaucoma, psychosis, dysmenorrhea, myopathy, neuropathy, thrombophlebitis, peptic ulcer, impaired wound healing, convulsions, local irritation (folliculitis, hypertrichosis, acne, hypopigmentation, macerations, dermal and epidermal atrophy, secondary infections, striae, miliaria).

Cortifoam Clinical Trials

See Literature

Cortifoam Note

Not Applicable

Cortifoam Patient Counseling

See Literature