Constipation and bowel cleansers:

Indications for: COLYTE w. FLAVOR PACKS

Bowel cleansing before colonoscopy or barium enema exam.

Adult Dosage:

After fasting for >3hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until fecal discharge is clear. Usual dose 3–4L. Only clear liquids until exam.

Children Dosage:

Not established.

COLYTE w. FLAVOR PACKS Contraindications:

GI obstruction or perforation. Gastric retention. Toxic colitis. Toxic megacolon. Ileus.

COLYTE w. FLAVOR PACKS Warnings/Precautions:

Not for direct ingestion. Correct fluid/electrolyte abnormalities prior to initiation. Increased risk of arrhythmias (eg, history of prolonged QT, uncontrolled arrhythmias, recent MI, unstable angina, CHF or cardiomyopathy); do pre-dose and post-colonoscopy ECGs. Severe ulcerative colitis. Semi- or unconsciousness. Impaired gag reflex. Swallowing abnormalities. Risk for aspiration or regurgitation. History of seizures. Rule out GI obstruction or perforation. Maintain adequate hydration. Renal impairment. Pregnancy. Nursing mothers.

COLYTE w. FLAVOR PACKS Classification:

Isosmotic bowel cleanser.

COLYTE w. FLAVOR PACKS Interactions:

Avoid concomitant with starch-based thickeners. Caution with drugs that increase risk of fluid/electrolyte abnormalities, arrhythmias or QT prolongation. Drugs administered within 1hr of start of Colyte may not be absorbed. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal, known or suspected hyponatremia: may increase risk of seizures. Concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Increased risk of ischemic colitis with concomitant stimulant laxatives.

Adverse Reactions:

Nausea, abdominal fullness or bloating, cramps, vomiting, anal irritation; serious: colonic mucosal ulceration, ischemic colitis; rare: arrhythmias.

How Supplied:

Pwd—4L (disposable jug w. 3 flavor packs)