Colyte W. Flavor Packs

  • Constipation and bowel cleansers

Colyte W. Flavor Packs Generic Name & Formulations

General Description

Polyethylene glycol 3350 60g, sodium chloride 1.46g, potassium chloride 0.745g, sodium bicarbonate 1.68g, sodium sulfate 5.68g, flavor 0.851g/pack (orange, lemon lime, cherry); per liter of soln; pwd for reconstitution (add 1 flavor pack before reconstitution).

Pharmacological Class

Isosmotic bowel cleanser.

How Supplied

Pwd—4L (disposable jug w. 3 flavor packs)


Colyte W. Flavor Packs Indications


Bowel cleansing before colonoscopy or barium enema exam.

Colyte W. Flavor Packs Dosage and Administration


After fasting for >3hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until fecal discharge is clear. Usual dose 3–4L. Only clear liquids until exam.


Not established.

Colyte W. Flavor Packs Contraindications


GI obstruction or perforation. Gastric retention. Toxic colitis. Toxic megacolon. Ileus.

Colyte W. Flavor Packs Boxed Warnings

Not Applicable

Colyte W. Flavor Packs Warnings/Precautions


Not for direct ingestion. Correct fluid/electrolyte abnormalities prior to initiation. Increased risk of arrhythmias (eg, history of prolonged QT, uncontrolled arrhythmias, recent MI, unstable angina, CHF or cardiomyopathy); do pre-dose and post-colonoscopy ECGs. Severe ulcerative colitis. Semi- or unconsciousness. Impaired gag reflex. Swallowing abnormalities. Risk for aspiration or regurgitation. History of seizures. Rule out GI obstruction or perforation. Maintain adequate hydration. Renal impairment. Pregnancy. Nursing mothers.

Colyte W. Flavor Packs Pharmacokinetics

See Literature

Colyte W. Flavor Packs Interactions


Avoid concomitant with starch-based thickeners. Caution with drugs that increase risk of fluid/electrolyte abnormalities, arrhythmias or QT prolongation. Drugs administered within 1hr of start of Colyte may not be absorbed. Drugs that may lower the seizure threshold (eg, tricyclic antidepressants), alcohol or benzodiazepine withdrawal, known or suspected hyponatremia: may increase risk of seizures. Concomitant diuretics, ACE inhibitors, ARBs, NSAIDs; may affect renal function. Increased risk of ischemic colitis with concomitant stimulant laxatives.

Colyte W. Flavor Packs Adverse Reactions

Adverse Reactions

Nausea, abdominal fullness or bloating, cramps, vomiting, anal irritation; serious: colonic mucosal ulceration, ischemic colitis; rare: arrhythmias.

Colyte W. Flavor Packs Clinical Trials

See Literature

Colyte W. Flavor Packs Note

Not Applicable

Colyte W. Flavor Packs Patient Counseling

See Literature