• Hyperlipoproteinemias

Colestid Generic Name & Formulations

General Description

Colestipol HCl 5g/pkt or scoop; granules; orange flavored (contains aspartame, phenylalanine) or unflavored.

Pharmacological Class

Bile acid sequestrant.

See Also

How Supplied

Unflavored 5g pkt—30, 90; Bulk—300g, 500g (w. scoop); Flavored 7.5g pkt—60; Bulk—450g (w. scoop); Tabs—120


Colestid Indications


Adjunct to diet to lower elevated serum total-C and LDL-C in primary hypercholesterolemia.

Colestid Dosage and Administration


5g–30g daily once or in divided doses mixed with liquid.


Not established.

Colestid Contraindications

Not Applicable

Colestid Boxed Warnings

Not Applicable

Colestid Warnings/Precautions


Obtain baseline serum cholesterol, LDL-C, and triglycerides, and monitor during therapy. Consider reducing dose, discontinuing, or alternative therapy if significant increase in triglycerides occur. May need Vit. A, D and K supplementation with long-term therapy. Exclude secondary causes of hypercholesterolemia (eg, hypothyroidism, diabetes, nephrotic syndrome, dysproteinemias, obstructive liver disease, alcoholism). Constipation; increase fluid/fiber intake or add a stool softener. Hemorrhoids. Phenylketonurics (flavored Colestid). Monitor thyroid function. Pregnancy. Nursing mothers.

Colestid Pharmacokinetics

See Literature

Colestid Interactions


Reduces absorption of folic acid, fat soluble vitamins, thiazides, furosemide, tetracycline, penicillin G, gemfibrozil, mycophenolic acid, others; monitor digitalis, propranolol; give other drugs at least 1hr before or 4hrs after. May affect absorption of oral phosphate supplements, hydrocortisone.

Colestid Adverse Reactions

Adverse Reactions

Constipation, fecal impaction, aggravated hemorrhoids, abdominal pain/cramp, gas, indigestion, heartburn, diarrhea, nausea, vomiting, Vit. A, D, K deficiencies or hyperchloremic acidosis with prolonged use.

Colestid Clinical Trials

See Literature

Colestid Note

Not Applicable

Colestid Patient Counseling

See Literature