Clomiphene Generic Name & Formulations
Clomiphene citrate 50mg; scored tabs.
Induction of ovulation.
Clomiphene Dosage and Administration
50mg daily for 5 days beginning on the 5th day of menstrual cycle; max 3 courses. If ovulation does not occur after 1st course, increase dose to 100mg daily for 2nd course; max 100mg/day for 5 days. See full labeling.
Primary ovarian failure. Ovarian cysts. Uterine leiomyomas. Abnormal uterine bleeding. Thrombophlebitis. Liver disease. Depression. Uncontrolled thyroid or adrenal dysfunction. Intracranial lesions. Pregnancy.
Clomiphene Boxed Warnings
Perform initial complete pelvic and endocrinologic exam. If ovarian enlargement occurs, hold dose until ovaries return to pretreatment size, and reduce dosage or duration of next course. Polycystic ovary syndrome. Discontinue if visual disorders occur. Metabolism disorders (eg, hypertriglyceridemia). Preexisting or family history of hyperlipidemia: monitor plasma triglycerides periodically. Nursing mothers.
Clomiphene Adverse Reactions
Ovarian enlargement, vasomotor flushes, abdominal/pelvic discomfort/distention/bloating, nausea, vomiting, breast discomfort, visual symptoms (eg, blurred vision, lights, floaters), headache, abnormal uterine bleeding; multiple births, pancreatitis.
Clomiphene Clinical Trials
Formerly known under the brand name Clomid, Serophene.
Clomiphene Patient Counseling