• Topical steroids

Clobex Generic Name & Formulations

General Description

Clobetasol propionate 0.05%; lotion.

How Supplied

Lotion—2oz, 4oz; Shampoo—4oz; Spray—2oz, 4.25oz

Clobex Indications


Corticosteroid-responsive dermatoses.

Clobex Dosage and Administration


Apply thin layer twice daily (AM & PM); max 50 g/week and 2 consecutive weeks' treatment per course. Moderate-to-severe plaque-type psoriasis: may use on up to 10% BSA for up to 4 consecutive weeks.


≤18yrs: not recommended.

Clobex Contraindications


Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).

Clobex Boxed Warnings

Not Applicable

Clobex Warnings/Precautions


Treat infection if present; discontinue if infection persists or worsens. Avoid contact with eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Increased risks of glaucoma, posterior subcapsular cataract. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy. Nursing mothers.

Clobex Pharmacokinetics

See Literature

Clobex Interactions

Clobex Adverse Reactions

Adverse Reactions

Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, visual symptoms, HPA axis suppression (esp. in children).

Clobex Clinical Trials

See Literature

Clobex Note

Not Applicable

Clobex Patient Counseling

See Literature