Clobex Spray

  • Topical steroids

Clobex Spray Generic Name & Formulations

General Description

Clobetasol propionate 0.05%.

How Supplied

Lotion—2oz, 4oz; Shampoo—4oz; Spray—2oz, 4.25oz

Clobex Spray Indications


Moderate-to-severe plaque psoriasis.

Clobex Spray Dosage and Administration


≥18yrs: Spray on twice daily (AM & PM), rub in gently and completely; max 50g/week and up to 4 consecutive weeks' treatment per course. May use on up to 20% BSA.


<18yrs: not recommended.

Clobex Spray Contraindications


Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).

Clobex Spray Boxed Warnings

Not Applicable

Clobex Spray Warnings/Precautions


Treat infection if present; discontinue if infection persists or worsens. Avoid contact with eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Increased risks of glaucoma, posterior subcapsular cataract. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy. Nursing mothers.

Clobex Spray Pharmacokinetics

See Literature

Clobex Spray Interactions

Clobex Spray Adverse Reactions

Adverse Reactions

Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, visual symptoms, HPA axis suppression (esp. in children).

Clobex Spray Clinical Trials

See Literature

Clobex Spray Note

Not Applicable

Clobex Spray Patient Counseling

See Literature