Clobetasol Propionate

  • Topical steroids

Clobetasol Propionate Generic Name & Formulations

General Description

Clobetasol propionate 0.05%; crm; oint; gel; soln for scalp application.

How Supplied

Contact supplier.

Clobetasol Propionate Indications


Corticosteroid-responsive dermatoses.

Clobetasol Propionate Dosage and Administration


Apply thin layer twice daily (AM & PM); max 50g/week or 50mL/week and 2 consecutive weeks' treatment per course.


Not recommended.

Clobetasol Propionate Contraindications


Do not use superpotent forms on face, groin, or axillae. Exclude viral disease (eg, chickenpox, measles).

Clobetasol Propionate Boxed Warnings

Not Applicable

Clobetasol Propionate Warnings/Precautions


Treat infection if present; discontinue if infection persists or worsens. Do not use near eyes, or on diaper dermatitis or pre-existing skin atrophy. Do not use fluorinated steroids longer than 1 week on the face. Avoid abrupt cessation in chronic use. Systemic absorption increased by broken or inflamed skin, prolonged use, application to large surface area, or use of occlusive dressings. Occlude only if necessary; do not occlude higher potency products. Monitor adrenal function in children if a high potency product or occlusion is used, and in adults if more than 50g weekly of a high potency product is used. Discontinue or reduce dose or potency if HPA axis suppression, Cushing's syndrome, hyperglycemia, glucosuria, or irritation occurs. Use lowest effective dose and potency (esp. in children). Use caution if applying to face or body folds. Do not use continuously or for prophylaxis. Foams are flammable. Reevaluate periodically. Pregnancy (Cat.C). Nursing mothers.

Clobetasol Propionate Pharmacokinetics

See Literature

Clobetasol Propionate Interactions

Clobetasol Propionate Adverse Reactions

Adverse Reactions

Burning, stinging, pruritus, erythema, skin atrophy, striae, miliaria, secondary infections, hypopigmentation, folliculitis, hypertrichosis, acneiform eruptions, dermal cracking and fissuring, telangiectasia, contact dermatitis, other local effects, immunosuppression, masks infections, HPA axis suppression (esp. in children).

Clobetasol Propionate Clinical Trials

See Literature

Clobetasol Propionate Note


Formerly known under the brand name Temovate, Temovate-E.

Clobetasol Propionate Patient Counseling

See Literature